Excellent Response to Palliative Chemotherapy for Pleural Recurrence of Uterine Papillary Serous Carcinoma.

Uterine papillary serous carcinoma (UPSC) is an aggressive variant of endometrial cancer. Though the majority of women with UPSC have high risk of recurrence, recurrence limited only to the pleural space has not been previously reported. It is also unusual for it to occur as late as 10 years after the initial treatment as it is usually very aggressive.

Cytologic features of pulmonary malakoplakia related to Rhodococcus equi in an immunocompromised host.

Cytologic features are described in bronchial brushings of a large cavitary lung mass from an immunosuppressed patient who had undergone liver transplantation. Scattered histiocytes with abundant eosinophilic, vacuolated cytoplasm were noted in a background of bronchial cells. Within approximately one fourth of the histiocytes, targetoid intracytoplasmic inclusions were present, consistent with Michaelis-Gutmann bodies.

Cytology of the thyroid gland: pitfalls in aspiration of the fibrotic nodule.

Fibrotic changes can be found in a variety of pathologic processes that affect the thyroid gland, and yet fine-needle aspiration (FNA) correlation of these lesions is not well-known. Cytologic findings are described from three different lesions, all with extensive fibrosis, that occurred in thyroid gland FNA. In each case, fibrotic changes resulted in cytologic changes potentially representing pitfalls in aspiration diagnosis.

Evaluation of the atypical cytologic smear. Validity of the 1991 Bethesda System.

The 1991 Bethesda System states that atypical squamous or glandular cells of undetermined significance should be further classified as reactive or premalignant/malignant. The validity of this qualification for identification of patients with cervical intraepithelial neoplasia (CIN) was tested. One hundred twenty-four cytologic smears with squamous atypia were reviewed retrospectively by two cytopathologists blind to the colposcopy results.