Publications by authors named "D B Crawford"
Background: Psychological safety is imperative for effective simulation-based learning within healthcare education, yet it is challenging for educators to establish. A visual tool, "Simulation Tool to Enhance Psychological Safety" (STEPS) was incorporated into simulation-based activities for prelicensure nursing students to support (or strengthen) psychological safety.
Objective: The purpose of this study was to determine the impact of the STEPS tool on psychological safety during simulated learning for prelicensure nursing students.
Article Synopsis
- * By analyzing data from the Million Veteran Program and other cohorts, the study identifies 63 genetic loci linked to AMD, including 30 that were previously unknown, highlighting significant differences in risk among various ancestries.
- * The findings reveal that certain genetic risk factors, like those found in the CFH locus, have varying effects based on ancestry, suggesting that targeted therapies could be developed by considering these genetic differences.
Article Synopsis
- - Therapeutic DNA cancer vaccines stimulate immune responses but often fall short in effectiveness; researchers found that manganese-doped silica nanoparticles (MSNA) can enhance these vaccines' performance.
- - When combined with plasmid DNA encoding cancer antigens like α-fetoprotein, MSNA significantly increased specific immune responses in animal models, leading to better cancer immunity.
- - The study showed that MSNA not only improved T cell responses against cancer but also successfully prevented tumor growth in models for both liver and HPV-related cancers.
Background: The genus Robinsonia DC. (tribe Senecioneae, Asteraceae) endemic to the Juan Fernández Islands in Chile is one of the most conspicuous insular plant groups in the world. Unlike typical herbaceous Asteraceae plants, these plants demonstrate spectacular and unusual rosette tree growth forms as shown by the alpine giant senecios (genus Dendrosenecio, tribe Senecioneae) endemic to the East African mountains.
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- TTN encodes the protein titin and is commonly associated with rare variants in patients diagnosed with atrial fibrillation (AF) during genetic testing.
- The study compared characteristics and outcomes of patients with AF having pathogenic TTN variants to those without such variants, revealing that TTN(+) patients experience more persistent AF and require more cardioversions.
- Findings indicate that nearly 50% of TTN(+) AF patients develop serious heart issues, emphasizing the importance of specialized evaluation and management for these individuals.