Microaerobic biodegradation of aromatic hydrocarbon mixtures: strategies for efficient nitrate and oxygen dosage.

The biodegradation of organic aromatic compounds in subsurface environments is often hindered by limited dissolved oxygen. While oxygen supplementation can enhance in situ biodegradation, it poses financial and technical challenges. This study explores introducing low-oxygen concentrations in anaerobic environments for efficient contaminant removal, particularly in scenarios where coexisting pollutants are present.

Activity of CDK4/6 inhibitors and parameters affecting survival in elderly patients in age-subgroups: Turkish Oncology Group (TOG) retrospective study.

Highly selective inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6is) have emerged as a standart of care for first- and second-line therapies in combination with endocrine therapy (ET) for HR+/HER2- metastatic breast cancer (MBC) patients. It has been reported that combination therapy is more effective than ET alone and is safe in elderly patients as well as young patients. Nevertheless, elderly and very old patients with HR+/HER2-MBC treated with CDK4/6 inhibitor (CDK4/6i) combinations are relatively underrepresented in randomized controlled trials.

The effects of sleep deprivation on the balance system: following normal sleep, 24 h of sleep deprivation, and rest under eyes-open and eyes-closed conditions.

Objective: This study investigated the effects of sleep deprivation (SD) on balance after normal sleep, 24 h of SD, and subsequent rest under eyes-open (EO) and eyes-closed (EC) conditions. Our aim was to ascertain whether the reduced efficiency of balance control following SD is generalized or selective.

Method: Nineteen participants (12 females, 7 males) completed the Pittsburgh Sleep Quality Index (PSQI).

Short-term effects of retinoic acid on the proliferation of SH-SY5Y cells via mitophagy and apoptosis.

Neuroblastoma shows the highest lethality in childhood and has poor prognosis at high grade. Our objectives included determining how retinoic acid affected the growth of neuroblastoma cells and the relationship between chemicals unique to neurons and cell death processes like apoptosis and mitophagy. The 50% inhibitory concentration of retinoic acid on SH-SY5Y neuroblastoma cells was determined at the 24th, 48th and 72nd hours.

Expression of concern: An 'on-demand' photothermal antibiotic release cryogel patch: evaluation of efficacy on an model for skin wound infection.

Expression of concern for 'An 'on-demand' photothermal antibiotic release cryogel patch: evaluation of efficacy on an model for skin wound infection' by Léa Rosselle, , , 2020, , 5911-5919, https://doi.org/10.1039/D0BM01535K.