Publications by authors named "D Asrat"

Background: Pseudomonas aeruginosa is one of the leading causes of nosocomial infections and the most common multidrug-resistant pathogen. This study aimed to determine antimicrobial resistance patterns, biofilm-forming capacity, and associated factors of multidrug resistance in P. aeruginosa isolates at two hospitals in Addis Ababa, Ethiopia.

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  • Healthcare in low- and middle-income countries is facing challenges due to the rise of multidrug-resistant bacteria, leading to increased illness and death.
  • A study conducted in Ethiopia identified 74 bacterial isolates from sepsis patients across four hospitals, revealing significant antimicrobial resistance and clonal patterns among the bacteria.
  • Findings highlight the urgency for enhanced infection control measures and improved use of antibiotics, as well as adopting advanced techniques for bacterial identification to combat these emerging threats.
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  • The study explores the prevalence of multidrug-resistant Pantoea species among sepsis patients in Ethiopia, highlighting the growing burden of sepsis caused by these pathogens.
  • Conducted from October 2019 to September 2020, researchers analyzed blood cultures from 1,416 patients across four hospitals, identifying various Pantoea species and characterizing them through advanced genomic techniques.
  • Findings revealed that P. dispersa was the most common, displaying genetic similarities and known antimicrobial resistance genes, emphasizing the need for improved infection control measures to combat these resistant strains.
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  • In Uganda, many women face unintended pregnancies and a lack of contraceptive methods, which can lead to health problems.
  • A study looked at data from 18,506 women and found that nearly 44.5% of pregnancies were unplanned, and about 21% of women needed better access to contraception.
  • It showed that women who have unmet contraceptive needs are nearly four times more likely to have unintended pregnancies, and other factors like age, education, and household wealth also play a role.
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Rabies is an important zoonosis in Ethiopia, where lack of research is cited as a constraint to implementation of the national rabies control strategy. We conducted a systematic review of publications and theses on rabies in Ethiopia, to document research gaps and areas of knowledge saturation in relation to geographic and species focus, methods and findings. We also examined funding sources and extent of local researcher participation.

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