Publications by authors named "D Ashley Price"
Inhibitory killer cell immunoglobulin-like receptors (iKIRs) are a family of inhibitory receptors that are expressed by natural killer (NK) cells and late-stage differentiated T cells. There is accumulating evidence that iKIRs regulate T cell-mediated immunity. Recently, we reported that T cell-mediated control was enhanced by iKIRs in chronic viral infections.
View Article and Find Full Text PDFBackground: Preserved ratio impaired spirometry (PRISm) represents a population with spirometry results that do not meet standardized COPD obstruction criteria, yet present with high respiratory symptom burden and might benefit from respiratory management and treatment. We aimed to determine prevalence of PRISm in US primary care patients diagnosed with COPD, describe their demographic, clinical, and CT scan characteristics.
Methods: An observational registry study utilizing the US APEX COPD registry, composed of patients diagnosed with COPD aged 35+ years.
Article Synopsis
- The microbiome plays a crucial role in host physiology, with well-known effects from bacteria, but less is understood about fungi's contributions.
- In a study on Hawaiian picture-wing flies, antifungal treatments negatively impacted female reproduction, while antibacterial treatments affected male fecundity differently.
- Combining both treatments led to significant reductions in reproduction and altered lipid metabolism, indicating the importance of microbial interactions for maintaining gut health and reproductive success.