[AL amyloidosis].

AL amyloidosis is a systemic disease caused by the deposition of fibrillar proteins in organs and tissues. These deposits are responsible for organic dysfunctions and may be rapidly lethal. Current therapy is unsatisfactory.

Nuclear DNA content, proliferation index and nuclear size determination in normal and tumoral adrenal tissues, pheochromocytomas and metastases.

The diagnostic values of nuclear size, proliferation index and ploidy level were investigated in a series of 58 samples from adrenal glands, including 9 samples from normal adrenal glands, 18 adenomas, 3 carcinomas, 16 pheochromocytomas and 12 metastases. Nuclear assessments were computed on Feulgen-stained nuclei by means of a cell image processor. Ploidy level was assessed by means of both the DNA index and DNA histogram type.

Carcinomas of the thyroid with unusual presentation. About two cases.

Two cases of thyroid carcinoma with unusual presentation are reported. In the first case, a follicular carcinoma was associated with hyperthyroidism from a hot nodule located in the same lobe. This condition is not so infrequent as indicated by the literature and should warrant pathological examination at the time of excision of the hot nodule.

DNA histogram typing in human seminomas.

Characterization of the nuclear DNA content (DNA index and DNA histogram type) was carried out in 9 normal testicular tissues and 21 seminomas. Proliferative activity was further determined in the seminomas. Nuclear DNA content was assessed by means of a cell image processor computing the integrated optical density on Feulgen-stained nuclei from formalin-fixed paraffin-embedded materials.

Cyst of the gallbladder.

A cyst of the gallbladder is a very rare lesion. The possible causes of such an anomaly are reviewed. It may be acquired or congenital.