[Long-term care facilities during the COVID-19 pandemic : Considerations on the way back to normality].

Long-term care facilities (LTCF) were and are particularly affected by the COVID-19 pandemic. The dimensions of the outbreaks and the high mortality among residents led to massive restrictions in LTCFs, especially in the area of social contacts and activities but also in areas of medical care. With the start of vaccinations and the improved testing options, the situation has now changed and existing restrictions must be evaluated to determine whether they are still appropriate.

Intratumoral DNA stem-line heterogeneity in superficial spreading melanoma.

Background: In primary melanomas, data on the degree of intratumoral heterogeneity to date have been lacking.

Objective: Our purpose was to investigate intratumoral DNA stem-line heterogeneity in superficial spreading melanoma (SSM).

Methods: Multiple measuring fields of 54 SSMs (tumor thickness median 1.