A Thematic Analysis of Couples' Sexual Well-Being Following a Recent Pregnancy Loss.

Pregnancy loss has been linked to poorer mental and relationship well-being. Given that strong sexual well-being is associated with better mental and physical health, understanding sexual well-being following a recent pregnancy loss may contribute to education and treatment models. Yet, little research has examined the effects of pregnancy loss on both couple members' sexual well-being.

A novel peptide-based tau aggregation inhibitor as a potential therapeutic for Alzheimer's disease and other tauopathies.

Introduction: As aggregation underpins Tau toxicity, aggregation inhibitor peptides may have disease-modifying potential. They are therefore currently being designed and target either the VQIVYK aggregation-promoting hotspot found in all Tau isoforms or the VQIINK aggregation-promoting hotspot found in 4R isoforms. However, for any Tau aggregation inhibitor to potentially be clinically relevant for other tauopathies, it should target both hotspots to suppress aggregation of Tau isoforms, be stable, cross the blood-brain barrier, and rescue aggregation-dependent Tau phenotypes in vivo.

Trajectories of sexual well-being and links with grief after a recent pregnancy loss: a dyadic longitudinal study.

Background: Pregnancy loss affects 1 in 4 women and is linked with poorer overall health and relationship outcomes. Despite sexual well-being's importance to health, how sexual well-being changes across time after a pregnancy loss and what might predict such changes, like perinatal grief, have never been examined, leaving practitioners and couples without knowledge of what to expect.

Aim: We aimed to examine (1) how sexual satisfaction, sexual desire, sexual distress, and perinatal grief change from 10 to 25 weeks postloss for both couple members; and (2) if perinatal grief levels at 10 weeks postloss predict sexual well-being trajectories.

Interpersonal emotion regulation during relationship conflict: Daily and longitudinal associations with couples' sexual well-being.

Relationship conflicts, which are common among committed couples, provoke negative emotions with implications for sexual well-being (i.e., satisfaction, desire, low distress).