Publications by authors named "D Alex Heckert"

: Research indicates that take-home naloxone (THN) is saving lives across rural Appalachia, but whether it also results in treatment for opioid use disorders (OUDs) remains unclear. This study involves a detailed qualitative analysis of interviews with 16 individuals who had overdosed on opioids 61 times to understand why a THN intervention does not routinely lead to OUD treatment. : This study builds upon a one-year (2018) qualitative study on community responses to opioid overdose fatalities in four adjacent rural counties in Western Pennsylvania.

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Cancer-associated fibroblasts (CAFs) execute diverse and complex functions in cancer progression. While reprogramming the crosstalk between CAFs and cancer epithelial cells is a promising avenue to evade the adverse effects of stromal depletion, drugs are limited by their suboptimal pharmacokinetics and off-target effects. Thus, there is a need to elucidate CAF-selective cell surface markers that can improve drug delivery and efficacy.

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This narrative literature review addresses grassroots interventions for alcohol use disorders as practiced in Mexican immigrant communities. These organic efforts are 24-hour AA groups, or , fourth and fifth step AA groups, , and . Literature was identified using PubMed and CINAHL and limited to works published from 2000 to 2018.

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Evidence-based practice within the criminal justice system has relied primarily on cumulative reports of reassaults or rearrests, especially in evaluating effectiveness of domestic violence (DV) interventions. We use a longitudinal sample of DV offenders arrested and referred to DV offender programs in four cities to examine complex multi-outcome patterns of violent and abusive behavior and trajectories between patterns over time. Offenders and their partners were surveyed at program intake and followed for 15 months (N = 550).

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Researchers and practitioners recognize the need to develop better prediction of abuse and reassault among men referred to batterer programs. Previous approaches have produced relatively weak predictions for primarily dichotomized "reassault versus no reassault" outcomes. The primary objective of this research was to improve prediction using multinomial logistic regressions with multiple outcomes and conditional factors.

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