Publications by authors named "D Abiya Chelliah"

This review examines India's legal framework governing natural product sales, focusing on challenges and solutions. It analyses key legislation, including the Drugs and Cosmetics Act, Food Safety and Standards Act, and Biological Diversity Act, while addressing jurisdictional overlaps among bodies like FSSAI and CDSCO. Case studies highlight intellectual property disputes, quality control, mislabelling, false advertising, and unauthorised sales, emphasising consumer safety and public health.

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Purpose: To assess the clinical utility of the clustered regularly interspaced short palindromic repeats/Cas12a-based RID-MyC assay in diagnosing Fungal Keratitis (FK) in cases where conventional smear and culture methods fail to identify the causative pathogen.

Methods: This retrospective case series included 5 patients with clinically suspected FK and negative smear and culture results who were evaluated in the Cornea Department at Aravind Eye Hospital, Coimbatore, India, between January 1, 2024, and March 31, 2024. The primary outcome was the diagnostic performance of the RID-MyC assay in detecting fungal nucleic acids in cases of suspected FK with negative smear and culture results.

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Robotic assisted laparoscopy is increasingly popular for primary ventral and incisional hernia repair. A variety of robotic techniques have been described. More data is needed to evaluate the indications and benefits of these approaches.

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Objective: This study evaluated the RID-MyC (Rapid Identification of Mycoses using clustered regularly interspaced short palindromic repeats [CRISPR]) assay, a CRISPR/Cas12a-based diagnostic tool, for its efficacy in diagnosing fungal endophthalmitis (FE) compared with panfungal polymerase chain reaction (PCR) and culture methods.

Design: A comparative cross-sectional study assessing the performance of the RID-MyC assay against established diagnostic modalities for FE.

Subjects: The study included 133 intraocular samples from 117 patients with suspected microbial endophthalmitis.

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Article Synopsis
  • Old Wallow is a coastal desert in Antarctica that is largely unexplored, and researchers studied how nutrients from a nearby elephant seal wallow impact the soil communities in this hyper-arid area.
  • The study found that while overall soil microbial communities were similar to other environments, there was a significant presence of unclassified taxa often associated with marine ecosystems.
  • Elevated nutrient levels and specific environmental factors, such as salinity and moisture, were identified as key drivers influencing community composition, indicating that the ecosystem could be sensitive to future environmental changes.
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