Family-Professional Collaborative Physical Therapy Intervention via Telehealth for Children with Developmental Disabilities: A Mixed-Method Feasibility Study.

Aims: To evaluate attendance rates, daily therapy engagement, parents' perceptions regarding feasibility, acceptability, family-centeredness, and individualized outcomes of a collaborative telehealth-based physical therapy intervention for children with disabilities.

Method: Mixed-method design involving 15 families and 17 children with disabilities (range age 4-90 months). Parents recorded time spent on home activities.

Development of small molecule non-covalent coronavirus 3CL protease inhibitors from DNA-encoded chemical library screening.

Variants of SARS-CoV-2 have continued to emerge across the world and cause hundreds of deaths each week. Due to the limited efficacy of vaccines against SARS-CoV-2 and resistance to current therapies, additional anti-viral therapeutics with pan-coronavirus activity are of high interest. Here, we screen 2.

Test-retest reliability and internal structure of the Brazilian version of the impact on participation and autonomy (IPA-Br4) for individuals with physical disabilities.

Background: Participation is considered a central outcome of rehabilitation and needs to be appropriately assessed from a perspective that values individual values and preferences. The Brazilian version of the Impact on Participation and Autonomy (IPA-Br4) is the only adequate instrument to assess participation from a subjective perspective in Brazil.

Objective: To investigate the test-retest reliability and internal structure (structural validity and internal consistency) of the digital version of IPA-Br4 for individuals with physical disabilities.

First records of the roughskin dogfish Centroscymnus owstonii in the greater Antilles, central Caribbean Sea, Western Atlantic Ocean.

The roughskin dogfish Centroscymnus owstonii, a deep-sea shark, has a patchy global distribution, with most knowledge stemming from incidentally captured specimens. Using a deep-sea remote lander video system, we observed multiple C. owstonii individuals alive on the footage at 1054 m off Little Cayman, Cayman Islands, Western Atlantic Ocean, marking, to our knowledge, the first record of the species in the Greater Antilles, central Caribbean Sea, while also adding a new species locality record for the Cayman Islands.

Food consumption of workers in an information technology company: randomized clinical study.

Introduction: The structure of the workplace, work relationships, accessibility and quality of food and time for meals reflect on individuals' eating habits.

Objectives: Analyze the changes in the diet of workers in relation to the consumption of calories, macronutrients and micronutrients.

Methods: Longitudinal study, lasting 8 months, randomized and descriptive clinical trial, with 95 information technology workers in the city of Campinas, state of São Paulo.