Publications by authors named "D A V Rosario"
Article Synopsis
- Contrast-enhanced dual-energy mammography (DEM) can detect tumors better in dense breast tissue than standard mammography, but traditional iodine-based contrast agents have significant limitations, including use restrictions and high doses.* -
- The study introduces ultrasmall molybdenum disulfide nanoparticles (MoS NPs) that are biocompatible and produce higher image contrast in DEM compared to conventional contrast agents like iopamidol.* -
- MoS NPs also show rapid elimination from the body, reducing concerns about long-term toxicity, which suggests they could effectively serve as dual-modality contrast agents for both DEM and CT imaging.*
Article Synopsis
- The study aimed to determine normal levels of cardiac troponin-I in stable newborns and see how factors like maternal diabetes, delivery method, and Apgar scores influence these levels.
- A total of 132 newborns were analyzed, with 119 for baseline troponin-I levels and 13 who were born to mothers with SARS-CoV-2.
- Results showed a mean troponin-I level of 0.019 ± 0.018 ng/mL in healthy newborns, with no significant differences based on maternal health or delivery method, while those born to mothers with SARS-CoV-2 had higher levels at 0.081 ± 0.1 ng/mL.
Objective: To report real-world outcomes for high-risk non-muscle-invasive bladder cancer (HRNMIBC), including bacillus Calmette-Guérin (BCG) and radical cystectomy (RC), as randomised comparisons of these have not been possible.
Methods: We detail consecutive participants screened for the BRAVO randomised controlled trial comparing RC with BCG (International Standard Randomised Controlled Trial Number [ISRCTN]12509361). Patients were prospectively registered and case-note review used for outcomes.
Article Synopsis
- NICE recommends supervised exercise for men with prostate cancer on ADT, but it’s not commonly implemented in NHS practice.
- The STAMINA programme aims to test how to effectively integrate these recommendations into NHS care through stakeholder workshops.
- Key themes from the workshops included the need for specialized training, engaging champions for the program, and establishing clear communication and monitoring systems to aid successful implementation.
Background: Screening is not recommended for prostate cancer in the UK. Asymptomatic men aged ≥50 years can request a prostate-specific antigen (PSA) test following counselling on potential harms and benefits. There are areas of clinical uncertainty among GPs, resulting in the content and quality of counselling varying.
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