The posttraumatic stress disorder (PTSD) Checklist for (; PCL-5) was designed and validated to track symptoms over the past month (PCL-5-M), yet an untested ad hoc weekly version (PCL-5-W) is commonly used to track changes during treatment. We used archival data of clinical trials for the treatment of PTSD in veterans to assess the construct validity of PCL-5-W. Both PCL-5-M and PCL-5-W were found to have configural measurement invariance across four consecutive administrations.
View Article and Find Full Text PDFAntibacterial resistance (ABR) poses significant challenges to combating infections worldwide. ABR drivers are interconnected, complicating identification of intervention points. Researchers need a systems-based perspective that considers interrelated drivers collectively.
View Article and Find Full Text PDFLand plant organellar genomes have extremely low rates of point mutation yet also experience high rates of recombination and genome instability. Characterizing the molecular machinery responsible for these patterns is critical for understanding the evolution of these genomes. While much progress has been made towards understanding recombination activity in land plant organellar genomes, the relationship between recombination pathways and point mutation rates remains uncertain.
View Article and Find Full Text PDFThere are two versions of the Cognitive Processing Therapy (CPT) protocol: one that includes a trauma narrative and one that does not. Despite both versions being used in clinical practice, to date, there has not been a comprehensive comparison of posttraumatic stress disorder (PTSD) treatment outcomes associated with these two protocols. The current study is a meta-analytic review of 29 randomized controlled trials of CPT+A (k = 13) and CPT-C (k = 16) in which we investigated whether there are differences in treatment outcome effect sizes and treatment dropout between the two protocol versions.
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