Estimation of phase distortions of the photoplethysmographic signal in digital IIR filtering.

Pre-processing of the photoplethysmography (PPG) signal plays an important role in the analysis of the pulse wave signal. The task of pre-processing is to remove noise from the PPG signal, as well as to transmit the signal without any distortions for further analysis. The integrity of the pulse waveform is essential since many cardiovascular parameters are calculated from it using morphological analysis.

Incoherent optical fluctuation flowmetry for detecting limbs with hemodynamically significant stenoses in patients with type 2 diabetes.

Introduction: The development of new highly accurate, inexpensive and accessible methods for the detection of lower-extremity peripheral artery disease (LE-PAD) in diabetic patients is required. The aim of this study was to evaluate the accuracy of a new incoherent optical fluctuation flowmetry (IOFF) method in detecting legs with hemodynamically significant stenoses compared to ankle brachial index (ABI) and transcutaneous oximetry (TcPO2) in patients with diabetes mellitus (DM).

Materials And Methods: Patients were recruited into 2 groups.

Impact of Chronic Oral Administration of Gold Nanoparticles on Cognitive Abilities of Mice.

The influence of gold nanoparticles after their prolonged oral administration to mice (during pregnancy and lactation) on spatial memory and anxiety levels in offspring was investigated. Offspring were tested in the Morris water maze and in the elevated Plus-maze. The average specific mass content of gold which crossed the blood-brain barrier was measured using neutron activation analysis and constituted 3.

Incoherent Optical Fluctuation Flowmetry: A New Method for the Assessment of Foot Perfusion in Patients with Diabetes-Related Lower-Extremity Complications.

(1) Background: To date, there are no studies evaluating the ability of the incoherent optical fluctuation flowmetry (IOFF) method to assess foot tissue perfusion. The aim of this study was to evaluate the correlation between perfusion values measured by IOFF and TcPO2 in patients with diabetes-related lower-extremity complications. (2) Methods: This was an observational, cross-sectional, two-center study.

Methods of Non-Invasive In Vivo Optical Diagnostics in the Assessment of Structural Changes in the Skin Induced by Ultraviolet Exposure in an Experimental Model.

Background: This paper demonstrates the use of optical diagnostic methods to assess the dynamic skin changes observed in acute and chronic exposure to ultraviolet (UV) radiation in vivo.

Methods: Firstly, in order to initiate photoaging (chronic UV exposure), animals ( = 40) were divided into two groups: chronic UV exposure ( = 30), and control ( = 10; without irradiation). Photoaging in animals was induced by chronic repeated exposure to UVA radiation three times per week, for 12 weeks continuously, while the UV dose increased stepwise over the course of the experiment (55 minimal erythema doses (MED) in total).