Corrigendum: Phenotypic and transcriptional characterization of LVS during transition into a viable but non-culturable state.

[This corrects the article DOI: 10.3389/fmicb.2024.

Phenotypic and transcriptional characterization of LVS during transition into a viable but non-culturable state.

is a gram-negative, intracellular pathogen which can cause serious, potentially fatal, illness in humans. Species of are found across the Northern Hemisphere and can infect a broad range of host species, including humans. Factors affecting the persistence of in the environment and its epidemiology are not well understood, however, the ability of to enter a viable but non-culturable state (VBNC) may be important.

Association of genetic variants and survival in patients with acute myeloid leukemia in rural Appalachia.

Background: Previous population health studies examining adults with acute myeloid leukemia (AML); however many of these, such as the Cancer Genome Atlas, are derived from databases collected by large urban centers. Due to its unique industry and environmental exposures, we hypothesized the West Virginia Appalachian population may have different mutational trends and clinical outcomes.

Aims: To address the concern of under-representation of rural minorities in cancer genomic databases, we performed exploratory whole exome sequencing in patients with newly diagnosed AML in rural Appalachia.

Differential Histone Posttranslational Modifications Induced by DNA Hypomethylating Agents.

Introduction: The prototype DNA hypomethylating agents 5-azacytidine (5AC) and decitabine (DAC) are currently FDA-approved for treatment of blood and bone marrow disorders like myelodysplastic syndrome. 5AC and DAC are considered similar drugs and were shown to induce histone modifications that modulate gene expression. The aim of this study is to compare the effect of both drugs on histone acetylation and methylation at multiple histone amino acids residues.

Role of and in Susceptibility to Resazurin.

The phenoxazine dye resazurin exhibits bactericidal activity against the Gram-negative pathogens and . One resazurin derivative, resorufin pentyl ether, significantly reduces vaginal colonization by in a mouse model of infection. The narrow spectrum of bacteria susceptible to resazurin and its derivatives suggests these compounds have a novel mode of action.