Publications by authors named "D A Pine"
Neural Rewiring of Resilience: The Effects of Combat Deployment on Functional Network Architecture.
Biol Psychiatry Cogn Neurosci Neuroimaging
January 2025
Background: Although combat-deployed soldiers are at a high risk for developing trauma-related psychopathology, most will remain resilient for the duration and aftermath of their deployment tour. The neural basis of this type of resilience is largely unknown, and few longitudinal studies exist on neural adaptation to combat in resilient individuals for whom a pre-exposure measurement was collected. Here, we delineate changes in the architecture of functional brain networks from pre- to post-combat in psychopathology-free, resilient participants.
View Article and Find Full Text PDFPast results suggest that fear extinction and the return of extinguished fear are compromised in adolescents. However, findings have been inconclusive as there is a lack of fear extinction and extinction retention studies including children, adolescents and adults. In the present study, 36 children (6-9 years), 40 adolescents (13-17 years) and 44 adults (30-40 years), underwent a two-day fear conditioning task.
View Article and Find Full Text PDFIndividual differences in how the brain responds to novelty are present from infancy. A common method of studying novelty processing is through event-related potentials (ERPs). While ERPs possess millisecond precision, spatial resolution remains poor, especially in infancy.
View Article and Find Full Text PDFArticle Synopsis
- The study examines how brain connectivity, both structural and functional, influences the development of mental health issues in adolescents.
- The research uses advanced MRI techniques to compare brain structure and activity, focusing on a group of youth with high symptom levels.
- Results suggest that stronger connections between certain brain networks are linked to increased negative emotions, which might hinder important brain changes needed for positive mental health outcomes during adolescence.
Introduction: Past work relates intelligence quotient (IQ) to risk for Post-Traumatic Stress Disorder (PTSD) among soldiers. We gathered data over multiple deployments to assess how IQ relates to the rate of symptom development both directly and through increasing the risk for traumatic combat exposure.
Methods: Male infantry soldiers from a maneuver brigade (N = 582) were followed over the 3-year period of their mandatory military service.