Publications by authors named "D A Pavlovich"
Coronavirus disease (COVID-19) has become a global pandemic. COVID-19 patients need immediate diagnosis and rehabilitation, which makes it urgent to identify new protein markers for a prognosis of the severity and outcome of the disease. The aim of this study was to analyze the levels of interleukin-6 (IL-6) and secretory phospholipase (sPLA2) in the blood of patients regarding the severity and outcome of COVID-19 infection.
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- The study investigates the role of genetic variants in the susceptibility and severity of COVID-19 using a large dataset (gnomAD) and a group of 37 Russian patients.
- It finds slight differences in allele frequencies among European populations, particularly noting that Southern Europeans have fewer missense variants.
- While common genetic variants do not significantly impact COVID-19 severity, some rare variants may influence disease outcomes, suggesting genetics play a role in varying COVID-19 severity.
Community engagement research is widely discussed but rarely implemented. This article describes the implementation of a community engagement research project on Dual Diagnosis Anonymous, a rapidly spreading peer support program in Oregon for people with co-occurring mental illness and substance use disorders. After three years of discussions, overcoming barriers, and involving several institutions, this grassroots research project has been implemented and is expanding.
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