Metastases of well-differentiated thyroid cancer to the gastrointestinal system.

Background: The incidence of distant metastases at the time of initial presentation of well-differentiated thyroid cancer is approximately 4%. During the course of treatment and follow-up, the prevalence of distant metastases ranges from 2% in low-risk patients up to 33% in high-risk patients. When present, distant metastases occur primarily in the lungs and, to a lesser extent, in bones.

Malignant Zollinger-Ellison syndrome: remission of primary and metastatic pancreatic tumor after gastrectomy: report of a case and review of the literature.

A patient with documented metastatic islet cell carcinoma of the pancreas and Zollinger-Ellison syndrome, with regression of tumor after total gastrectomy is described. Pertinent similar cases are summarized further suggesting that gastrectomy may have a role in the management of the tumorous as well as the acid-secretory features of this disease.