Publications by authors named "D A Jewell"

Article Synopsis
  • The study aimed to investigate genetic variants of the AGXT2 gene in cats, focusing on their serum chemistries and how these relate to the formation of uroliths (kidney stones).
  • Researchers analyzed data from 445 cats, assessing their genotypes, metabolic profiles, and history of stone incidence, ultimately identifying significant metabolites linked to urolith formation.
  • Findings revealed that cats with the AA variant of the AGXT2 gene were more likely to develop stones, had a higher incidence of chronic kidney disease, and experienced a shorter lifespan, highlighting the role of specific metabolites in differentiating between stone formers and non-stone formers.
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The effect of digestive bypass macronutrients and age on stool quality (moisture and firmness) in dogs and cats is not well understood. Data were analyzed from digestibility tests ( = 2020, 361 dogs and 536 cats) including dry and wet product types. Both food and feces were measured for moisture and nutrients according to standard protocols; stool firmness was graded.

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Article Synopsis
  • Gallbladder disease in dogs, specifically mucocele formation, is linked to abnormal lipid metabolism and is characterized by unusual mucus secretion.
  • A study involving 18 affected dogs and 18 controls utilized lipid analysis techniques to investigate potential causes of the disease.
  • The research found a distinctive lipid profile in affected dogs with increased lipogenesis, suggesting that altered lipid metabolism plays a key role in the development of gallbladder mucocele formation.
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