A protocol to build soil descriptions for APSIM simulations.

Soil processes have a major impact on agroecosystems, controlling water and nutrient cycling, regulating plant growth and losses to the wider environment. Process-based agroecosystem simulation models generally encompass detailed descriptions of the soil, including a wide number of parameters that can be daunting to users with a limited soil science background. In this work we review and present an abridged description of the models used to simulate soil processes in the APSIM (Agricultural Production Systems sIMulator) framework.

Scope for improved eco-efficiency varies among diverse cropping systems.

Global food security requires eco-efficient agriculture to produce the required food and fiber products concomitant with ecologically efficient use of resources. This eco-efficiency concept is used to diagnose the state of agricultural production in China (irrigated wheat-maize double-cropping systems), Zimbabwe (rainfed maize systems), and Australia (rainfed wheat systems). More than 3,000 surveyed crop yields in these three countries were compared against simulated grain yields at farmer-specified levels of nitrogen (N) input.

Adequacies and inadequacies in assessing murine toxicity data with antineoplastic agents.

Previous retrospective analyses have suggested a very positive correlation in toxic doses of antineoplastic agents between mice and humans. Additional toxicological information has now been accumulated and reveals a noticeable variability in the existing data base. Nevertheless, it is likely that mouse toxicological studies will become a principal determinant for estimating initial doses to be used in humans.