Publications by authors named "D A Haering"

In pursuit of higher activity and stability of electrocatalysts toward the oxygen reduction reaction, it has become standard practice to alloy platinum in various structural configurations. Transition metals have been extensively studied for their ability to tune catalyst functionality through strain, ligand, and ensemble effects. The origin of these effects and potential for synergistic application in practical materials have been the subject of many theoretical and experimental analyses in recent years.

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Postpartum hemorrhage is a relatively common and highly morbid complication of the postpartum period that often requires management by specialized providers at tertiary care facilities. Critical care transport teams may be tasked with transporting postpartum patients who are already experiencing postpartum hemorrhage, but they should also be aware that other peripartum patients may be at risk for developing postpartum hemorrhage while in the process of transport. As such, it is imperative that transport providers understand the signs, symptoms, causes, and complications of postpartum hemorrhage as well as the options for intervention and treatment.

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Purpose: Postural control impairment has been identified as a potential extrarespiratory manifestation in patients with chronic obstructive pulmonary disease (COPD). The aims of this study were to identify clinical factors that characterize patients with reduced postural control, to examine the correlation between clinical factors and postural control and to determine predictors of an impaired postural control among COPD participants enrolled in a pulmonary rehabilitation (PR) program.

Methods: This study is a secondary analysis of an observational study (PARACHUTE).

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Purpose: Impairment of postural control is common in people with COPD. However, the precise characteristics of this alteration are not clearly known. The "Systems Framework for Postural Control" which define postural control sub-components, represents an interesting tool to explore this field.

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Article Synopsis
  • KRAS is a key oncogenic driver in cancers and relies on protein-protein interactions (PPIs) for its signaling, especially with SOS1 for activation.
  • A study found that adding just one atom between specific residues in SOS1 can turn the SOS1 activators into inhibitors.
  • This new method, which utilizes small modifications rather than large molecules, shows promise in inhibiting challenging PPIs like SOS1-KRAS, especially when combined with the EGFR inhibitor afatinib to target KRAS mutant colorectal tumors.
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