[Incidence of chromosome aberrations in the bone marrow of monkeys and their progeny after exposure to aflatoxin B1].

A mutagenic effect of aflatoxin B1 (AFB1) was studied in somatic cells of primates. It is shown that AFB1 elevates the chromosome aberration frequency in bone marrow cells of two monkey species: Macaca mulatta and Papio hamadryas. Genome mutations were found in these experimental primates simultaneously with chromosome aberrations.

Frequency of chromosome aberrations in bone marrow of monkeys and their F1 after aflatoxin B1 injection.

A mutagenic effect of aflatoxin B1 (AFB1) in somatic cells of primates is investigated. It is shown that AFB1 elevated the frequency of chromosome aberrations in the bone marrow of two species of monkeys: Macaca mulatta and Papio hamadryas. Beside chromosome aberrations, genome mutations were found in these experimental primates.

[Rous virus-induced sarcoma study of Macaca mulatta monkeys].

The Carr-Zilber strain of Rous sarcoma virus is highly oncogenic for adult monkeys of the species Macaca mulata. In the present study the authors examined some characteristics of tumor growth, when the tumor either regressed or progressed until it killed its host. The kinetics of antibody formation to antigens coded as CZ-RSV was followed in animals with a different course of tumor disease.

Characterization of tumors induced in adult Macaca mulata monkeys with Carr-Zilber strain of Rous sarcoma virus.

The Carr-Zilber strain of Rous sarcoma virus is highly oncogenic for adult monkeys of the species Macaca mulata. In the present study, we examined some characteristics of tumor growth when the tumor either regressed or progressed until it killed its host. We followed the kinetics of antibody formation to antigens coded by CZ-RSV in animals with a different course of tumor disease.