Respiratory syncytial virus (RSV) is a leading cause of respiratory infections, particularly affecting young infants, older adults, and individuals with comorbidities. : This document, developed as a consensus by an international group of experts affiliated with the World Association of Infectious Diseases and Immunological Disorders (WAidid), focuses on recent advancements in RSV prevention, highlighting the introduction of monoclonal antibodies (mAbs) and vaccines. : Historically, RSV treatment options were limited to supportive care and the monoclonal antibody palivizumab, which required multiple doses.
View Article and Find Full Text PDFBackground: Respiratory syncytial virus (RSV) infection in the first year of life has been linked with an increased risk for asthma. Some propose that RSV-induced inflammation leads to lasting airway changes, while others contend that RSV bronchiolitis is a marker for underlying predisposition. Social distancing adopted during the COVID-19 pandemic has led to a dramatic reduction in RSV activity, providing an unexpected opportunity to investigate this debate.
View Article and Find Full Text PDFIntroduction Low testosterone (T) is linked with frailty, which predicts poor postoperative recovery across many surgical procedures. Therefore, low T may impact perioperative outcomes for surgical patients. We sought to characterize the association between low T, frailty, and perioperative outcomes in patients undergoing transurethral resection of the prostate (TURP) and laser photovaporization of the prostate (PVP).
View Article and Find Full Text PDFSecondary sexual characteristics, and the extent to which they are expressed, can convey information about the signaller. The blue scrotum and red penis of male vervet monkeys (Chlorocebus pygerythrus) make them a good species in which to examine inter- and intramale variation in signal expression. We quantified genital hue and luminance of male vervets at Lake Nabugabo, Uganda from standardized photos of male genitalia taken in May to June 2016, January to March 2019, and April to June 2019 to examine how dominance rank, fecal androgens (fARMs), fecal glucocorticoids (fGCMs), and parasitism related to achromatic (i.
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