Publications by authors named "D A G van Toor"

Background: In developing countries, the treatment outcomes of Burkitt lymphoma are poor due to the poorly equipped healthcare systems. In addition, there is limited comprehensive data within the African continent, including Kenya, about the outcomes of treatment for this cancer.

Aims: To assess treatment outcomes and variables associated with an increased risk of death from disease progression or treatment-related toxicities among Burkitt lymphoma pediatric patients at the Kenyatta National Hospital (KNH).

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Background: Rheumatic heart disease (RHD) remains a persistent public health challenge, particularly prevalent in developing and underdeveloped regions despite concerted global eradication efforts. The progressive stage of RHD, marked by valvular calcification, necessitates the imperative need to identify prognostic biomarkers. Fetuin-A, well-known for its role as a negative inhibitor of ectopic calcification, is investigated in our study as a potential biomarker for cardiac valve calcification in RHD patients.

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Article Synopsis
  • There is a growing number of cancer cases prompting research into its causes, which has led to new targeted immunotherapy strategies that aim to reduce the negative effects of traditional chemotherapy and radiotherapy.
  • Various targeted immunotherapies have been tested for their effectiveness, such as vaccines that use specific tumor-related antigens, checkpoint blockade therapies involving monoclonal antibodies, and adoptive cell transfer methods like CAR-T cell therapies.
  • The text reviews recent progress in these targeted immunotherapeutic strategies while also discussing their limitations in treating cancer.
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Ethnopharmacological Relevance: Psoriasis, a widespread skin condition impacting over 100 million individuals globally, is characterised by uncontrolled hyperproliferation of keratinocytes, abnormal apoptosis, and excessive secretion of inflammatory cytokines and angiogenic factors. Traditional use of Alstonia scholaris (L.) R.

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