Publications by authors named "D A Frolov"
Introduction: Bone morphogenic protein-2 (BMP-2) is a potent growth factor cytokine, with indications for interbody spinal fusion surgery and open tibial shaft repairs due to its osteoinductive properties. Off-label usage of BMP-2 has been documented; however, there are limited studies regarding the efficacy of using BMP-2 in non-union humeral shaft fractures.
Case Report: We present a case of a comminuted left humeral shaft fracture with pseudoarthrosis in a 64-year-old woman.
Article Synopsis
- Stem cell technology is pivotal in regenerative medicine, utilizing stem/progenitor cells for repairing or replacing damaged tissues to treat various diseases like cardiovascular and neurological disorders.
- Cell therapy works through two main mechanisms: the replacement of damaged tissue and the release of biologically active molecules that aid in tissue regeneration, but challenges like transportation complexity and immune rejection exist.
- The study focuses on the beneficial effects of proteins secreted by glial progenitor cells, showing they can reduce inflammation and support neuron survival by inhibiting harmful factors and maintaining cellular health, potentially paving the way for new therapeutic applications.
Functional organization of 3D plant thylakoid membranes as seen by high resolution microscopy.
Biochim Biophys Acta Bioenerg
November 2024
In the field of photosynthesis, only a limited number of approaches of super-resolution fluorescence microscopy can be used, as the functional architecture of the thylakoid membrane in chloroplasts is probed through the natural fluorescence of chlorophyll molecules. In this work, we have used a custom-built fluorescence microscopy method called Single Pixel Reconstruction Imaging (SPiRI) that yields a 1.4 gain in lateral and axial resolution relative to confocal fluorescence microscopy, to obtain 2D images and 3D-reconstucted volumes of isolated chloroplasts, obtained from pea (Pisum sativum), spinach (Spinacia oleracea) and Arabidopsis thaliana.
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- Coccydynia, or coccyx pain, often resolves on its own but can require treatments like NSAIDs, physical therapy, or a coccygectomy if severe symptoms persist.
- A new proposed method for coccygectomy — the paramedian approach — aims to reduce infection rates and improve healing by placing the incision further from the anus.
- A study of 41 patients who underwent this technique showed promising results, with evaluations of infection rates and patient satisfaction conducted post-surgery.
Introduction: Acute exertional compartment syndrome (AECS) is a condition with the potential for devastating outcomes if not promptly treated. Physicians must maintain a high index of suspicion when evaluating patients presenting with pain, swelling, decreased range of motion, and numbness within a muscle compartment. However, AECS is frequently misdiagnosed due to a multitude of factors, leading to a delay in treatment.
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