A medical mission volunteer bears witness to nightmarish inequalities.
View Article and Find Full Text PDFPlasma membrane (PM) expression of G-protein coupled receptors (GPCRs) is required for activation by extracellular ligands; however, mechanisms that regulate PM expression of GPCRs are poorly understood. For some GPCRs, such as alpha2c-adrenergic receptors (alpha(2c)-ARs), heterologous expression in non-native cells results in limited PM expression and extensive endoplasmic reticulum (ER) retention. Recently, ER export/retentions signals have been proposed to regulate cellular trafficking of several GPCRs.
View Article and Find Full Text PDFBACKGROUND: Improvements in breast cancer treatment and early diagnosis are leading to increasing numbers of breast cancer survivors, many of whom are experiencing upper limb lymphoedema as a post-treatment outcome. Current management techniques of breast cancer-related lymphoedema produce uneven results, signifying a need for research in this area. AIMS: To assess the symptom management practices of breast cancer survivors experiencing cancer-related lymphoedema by identifying and quantifying self-care management practices.
View Article and Find Full Text PDFSuccessful cleft palate repair (palatoplasty) was accomplished in a male canine pup from a kindred with autosomal recessive transmission for a complete cleft palate phenotype. This case represents the potential application of a new animal model for cleft palate repair. This reproducible congenital defect provides a clinically relevant model to improve research into the human anomaly, as compared with previous iatrogenic or teratogenically induced animal models.
View Article and Find Full Text PDFThe concept of a majority population in America is rapidly giving way to a collection of minority populations. To ensure representative study sample populations, nurse researchers must gain the ability to access many culturally and ethnically diverse groups. By examining common challenges to recruitment, many of the pitfalls of minority recruitment may be avoided.
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