Publications by authors named "D A Culp"

Article Synopsis
  • - The study investigates how the LrgAB system affects the fitness of bacteria in a dual-species mouse caries model, finding that specific mutants had different levels of colonization and caries severity compared to wild-type bacteria when the diet was adjusted to reduce sucrose exposure.
  • - By replacing sucrose with sterile water in the experiment, researchers were able to show that the previously masked contributions of LrgAB to bacterial competition and caries potential became clear, highlighting the importance of the Cid/Lrg system in environmental adaptability and caries development.
  • - The findings suggest that understanding the response of cariogenic bacteria to environmental changes is crucial for developing strategies to combat dental caries, as the bacteria can form complex biofilm communities
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The processes involved in regeneration of cutaneous compared to corneal tissues involve different intrinsic mechanisms. Importantly, cutaneous wounds involve healing by angiogenesis but vascularization of the cornea obscures vision. Previous studies showed that topically applied calreticulin (CALR) healed full-thickness excisional animal wounds by a tissue regenerative process markedly enhancing repair without evoking angiogenesis.

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Aims: We evaluated two species of human oral commensal streptococci in protection against dental caries induced by Streptococcus mutans.

Methods And Results: Candidate probiotics, Streptococcus sp. A12, Streptococcus sanguinis BCC23 and an arginine deiminase mutant of BCC23 (∆arcADS) were tested for their ability to reduce S.

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Mint oil is a key source of natural flavors with wide industrial applications. Two unbalanced polyploid cultivars named Native (Mentha Spicata L) and Scotch (M. × gracilis Sole) are the main producers of spearmint type oil, which is characterized by high levels of the monoterpenes (-)-carvone and (-)-limonene.

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