Publications by authors named "D A Carusi"
Objective: To evaluate the comparative efficacy of two of the most commonly used second-line uterotonics-methylergonovine maleate and carboprost tromethamine.
Methods: We conducted a double-blind randomized trial at two large academic perinatal centers in patients undergoing nonemergency cesarean delivery with uterine atony refractory to oxytocin, as diagnosed by the operating obstetrician. The intervention included administration of a single dose of intramuscular methylergonovine or carboprost intraoperatively at diagnosis.
Introduction: The aim of this study is to document the distribution of classic versus non-classic presentation of Placenta Accreta Spectrum (PAS) disorders as well as grading categories by the Society for Pediatric Pathology (SPP) and FIGO systems in an institutional cohort of gravid hysterectomies. We also document the prevalence of uterine scar as a histologic correlate for uterine scar dehiscence, a phenomenon raised by some as central to PAS pathogenesis.
Methods: PAS cases were assigned grade and designated as classic (anterior lower uterine segment implantation, prior C-section) or non-classic (implantation away from anterior lower uterine segment and/or no prior C-section).
Article Synopsis
- Cesarean hysterectomy is often thought to improve maternal health in cases of placenta accreta, but newer uterine-sparing techniques may help preserve fertility while reducing complications.
- Despite the interest in future pregnancies among patients, there's a lack of data on outcomes after conservative management of placenta accreta.
- A systematic review of 5 studies revealed that recurrence of placenta accreta in subsequent pregnancies was 11.8%, with some complications occurring post-delivery, emphasizing the need for more research in this area.
Objective: To identify independent risk factors for placenta accreta spectrum among pregnancies conceived with assisted reproductive technology.
Design: Retrospective cohort study.
Setting: Tertiary hospital.