Publications by authors named "D A Carone"
Background: Identifying eloquent regions associated with poor outcomes based on CT perfusion (CTP) may help inform personalized decisions on selection for endovascular therapy (EVT) in patients with large vessel occlusion (LVO) ischemic stroke. This study aimed to characterize the relationship between CTP-defined hypoperfusion and National Institutes of Health Stroke Scale (NIHSS) subitem deficits.
Methods: Patients with anterior circulation LVO, baseline CTP, itemized NIHSS at presentation and 24 hours were included.
Human satellitess(HSats) are pericentric, tandemly repeating satellite DNA sequences in the human genome. While silent in normal cells, a subset of HSat2 noncoding RNA is expressed and accumulates in the nucleus of cancer cells. We developed a FISH-based approach for identification of the distribution of three subfamilies of HSat2 (A1, A2, B) sequences on individual human chromosomes.
View Article and Find Full Text PDFArticle Synopsis
- The STAIR XII workshop focused on improving neuroimaging techniques for diagnosing acute ischemic stroke, bringing together experts from academia, industry, and government to identify key priorities.
- Ten critical areas were outlined for advancements, including enhancing imaging at stroke centers, refining clot analysis, and establishing criteria to predict treatment response.
- Despite progress in imaging for stroke treatment, significant challenges persist, highlighting the need for collaboration among academics, industry, and regulators to enhance technologies and improve patient outcomes.