Publications by authors named "Czuzoj-Shulman N"
Article Synopsis
- The study investigates the link between endometriosis during pregnancy and negative health outcomes for mothers and newborns, using data from the Healthcare Cost and Utilization Project over a 20-year period.
- Findings show a significant increase in endometriosis prevalence during pregnancy and reveal that mothers with endometriosis face higher risks of complications such as pre-eclampsia, gestational diabetes, and preterm birth, while their newborns may experience growth restrictions and congenital anomalies.
- The study emphasizes the need for healthcare providers to monitor pregnancies of individuals with endometriosis closely due to the heightened risk of adverse events associated with this condition.
Article Synopsis
- The study investigates the effects of Guillain-Barré syndrome (GBS) on maternal and fetal/neonatal outcomes during pregnancy, using data from the U.S. between 1999 and 2015.
- Findings showed a low incidence of GBS among pregnancies (2.1/100,000 births) but highlighted a rising trend in cases over the years.
- Pregnancies complicated by GBS were linked to higher risks of issues like preeclampsia, sepsis, postpartum hemorrhage, and higher rates of cesarean deliveries, indicating a need for close monitoring of affected pregnant women.
Article Synopsis
- Over the past few decades, cesarean delivery has been recommended as the safest option for breech presentations, and this study compares outcomes between planned vaginal births and planned cesarean births for breech fetuses.
- The study, using data from 2008 to 2017 involving over 546,000 breech deliveries, found that only 26.14% of planned vaginal births were successful, with significant risks associated with these deliveries.
- The results indicate that planned vaginal births for breech presentations have a low success rate and are linked to increased neonatal morbidity and mortality, suggesting that women should be thoroughly informed about the risks involved.
Objective: The incidence of Lyme disease (LD) infections has risen in recent decades. Gestational LD has been associated with adverse pregnancy outcomes; however, the results have been contradictory. The study objective was to examine the effects of gestational LD on obstetrical and neonatal outcomes.
View Article and Find Full Text PDFAmniotic fluid embolism: 20-year incidence and case-fatality trends in the United States.
Eur J Obstet Gynecol Reprod Biol
March 2024
Article Synopsis
- * AFE incidence was consistent at about 4.9 cases per 100,000 deliveries, while the case-fatality rate showed a decline to an average of 17.7%.
- * Higher AFE rates and fatalities were observed in women aged 35 and older, African-Americans, and those in urban-teaching hospitals, indicating a need for further research on diagnosis and treatment strategies.
Article Synopsis
- The study analyzes Robin sequence (RS) over a 20-year period using a large birth cohort from the HCUP-KID database, highlighting gaps in existing literature.
- The incidence of RS was found to be 5.15 per 10,000 births, with 63.3% classified as isolated RS and 36.7% as syndromic RS, showing higher rates of cardiac and neurological anomalies in RS patients.
- Syndromic RS patients experienced significantly worse outcomes, including higher mortality (14.1%) and tracheostomy rates (6.2%), compared to those with isolated RS, indicating implications for clinical management.
Obstetrical and neonatal outcomes among pregnancies complicated by hyperparathyroidism.
J Matern Fetal Neonatal Med
December 2023
Purpose: Severe hypercalcemia resulting from hyperparathyroidism may result in adverse perinatal outcomes. The objective of this study was to evaluate maternal and neonatal outcomes among pregnant women with hyperparathyroidism using a population database.
Methods: A retrospective cohort study was conducted using data from the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample from 1999-2015.
Article Synopsis
- * An analysis of 13,791,605 delivery hospitalizations from 1999 to 2015 found that 11,152 cases involved CSMM, leading to a mortality rate of 4.44 per 100 cases, although the overall case-fatality decreased over the years.
- * Key factors associated with increased mortality from CSMM included being Black or Hispanic, having Medicaid insurance, experiencing postpartum hemorrhage, or having conditions like systemic lupus erythematosus.
Purpose: Vulvodynia and vaginismus are common chronic vulvar pain disorders for which there is a paucity of literature on pregnancy outcomes of affected women. The study objective was to evaluate the associations between vulvodynia and vaginismus and obstetric outcomes.
Methods: We performed a retrospective cohort study including all birth-related admissions from 1999 to October 2015 extracted from the Healthcare Cost and Utilization Project-National Inpatient Sample from the United States.
Objective: To evaluate whether the increased risk of breast cancer is dependent on the formulation of menopausal hormone therapy (HT) used.
Methods: We performed a population-based case-control study of women aged 50 years or older using data from the U.K.
Article Synopsis
- The study examines how prior chemotherapy affects maternal and newborn health among cancer survivors seeking obstetrical care, with a focus on outcomes from 2006 to 2015.* -
- Out of over 7.9 million birth admissions, only 613 had a history of chemotherapy, revealing a rising trend in chemotherapy exposure among pregnant women.* -
- Findings indicate that women with a chemotherapy background faced more maternal complications and higher mortality risks, but there were no significant differences in adverse neonatal outcomes.*
Purpose: To identify risk factors associated with bladder injury during cesarean delivery, and to determine the frequency of associated morbidities.
Methods: Data obtained from the United States' Health Care Cost and Utilization Project-Nationwide Inpatient Sample were used to conduct a retrospective population-wide cohort study. ICD-9 codes were used to identify women who underwent a cesarean delivery between 1999 and 2015.
Article Synopsis
- The study investigates how inflammatory myopathies (IM) affect pregnancy outcomes for mothers and their newborns, addressing a gap in existing research.
- Using data from a large inpatient sample (1999-2015), the study finds that among nearly 14 million pregnant women, only 308 had IM, with increasing prevalence over time.
- Results reveal that women with IM face higher risks of complications like preeclampsia and infections, while their infants are more likely to experience prematurity and growth issues, suggesting a need for specialized care during these pregnancies.
Effect of hidradenitis suppurativa on obstetric and neonatal outcomes.
J Matern Fetal Neonatal Med
December 2022
Purpose: Hidradenitis suppurativa (HS) is a debilitating chronic inflammatory skin disease with an often-unsatisfactory response to treatment. The objective was to evaluate the association between HS and pregnancy, delivery and neonatal outcomes.
Methods: The United States' Healthcare Cost and Utilization Project-Nationwide Inpatient Sample database was used to conduct a retrospective cohort study among all women who delivered between 1999 and 2015.
Maternal and neonatal outcomes of births to women with psoriasis: a population-based cohort of 13 million births.
J Matern Fetal Neonatal Med
December 2022
Article Synopsis
- This study investigates the impacts of psoriasis on maternal and newborn outcomes during pregnancy, addressing gaps in existing research.* -
- It analyzed data from a large cohort of over 13 million pregnancy admissions, finding that women with psoriasis face higher risks for conditions like preeclampsia, gestational diabetes, and cesarean delivery.* -
- The study concludes that women with psoriasis require careful monitoring during pregnancy due to increased risks for both maternal and newborn complications.*
Background: The rate of cesarean delivery has increased in the United States over the last several decades. However, the rate of cesarean delivery on maternal request remains undetermined, and recent data on cesarean delivery on maternal request are lacking.
Objective: This study aimed to describe the prevalence and temporal trends of cesarean delivery on maternal request in the United States and characterize the population of women who elect to undergo a cesarean delivery in the absence of fetal or maternal indications.
Objectives: Acute pancreatitis is a rare condition that can be associated with significant complications. The objective of this study is to evaluate the maternal and newborn outcomes associated with acute pancreatitis in pregnancy.
Methods: A retrospective cohort study using the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample from the United States was performed.
Article Synopsis
- Obstructive sleep apnea (OSA) is associated with various health issues and may negatively affect pregnancy outcomes.
- A study analyzing over 7.9 million deliveries from 2006 to 2015 found that the prevalence of OSA among pregnant women increased significantly, leading to higher risks of conditions like preeclampsia, eclampsia, and complications during delivery.
- The research highlights that babies born to mothers with OSA are at a greater risk for prematurity and congenital abnormalities, emphasizing the need for careful monitoring of these high-risk pregnancies.
Purpose: We sought to describe temporal trends in hospital admissions for threatened preterm labor (TPTL) and to examine hospital admission duration among women delivered or discharged undelivered.
Methods: We carried out a cohort study on all TPTL admissions among pregnancies with a live singleton fetus and intact membranes between 1999 and 2015 using the United States' Healthcare Cost and Utilization Project-Nationwide Inpatient Sample. ICD-9 codes were used to identify women with TPTL.
Introduction: Cleft palate is amongst the most common birth defect across the world. Although its etiology is multifactorial, including genetic and environmental contributors, the investigators were interested in exploring whether its incidence was changing over time.
Methods: The Nationwide Inpatient Sample database, the largest publically available healthcare database in the United States, was used to identify all primary palatoplasties performed under 2 years of age and births which occurred over a 17-year period from 1999 to 2015.
Article Synopsis
- This study investigates how lipid metabolism disorders (LMD) affect pregnancy outcomes, focusing on both maternal and fetal health.
- It analyzed data from over 13 million births between 1999 and 2015, revealing that LMDs are linked to higher risks of complications such as diabetes, hypertension, and maternal death.
- The findings highlight the need for specialized prenatal care and counseling for women with LMDs due to the increased risks of adverse outcomes for both mothers and infants.
Purpose: Increased body mass index (BMI) is an independent risk factor for stillbirth. The purpose of this study was to determine an optimal time of delivery at term in obese women in order to decrease the risk of stillbirth in this population.
Methods: We conducted a retrospective population-based cohort study using the CDC's Period Linked Birth-Infant Death and Fetal Death data.
Characteristics and outcomes among pregnant women with end-stage renal disease on hemodialysis.
J Matern Fetal Neonatal Med
December 2022
Purpose: Pregnancy among women with end-stage renal disease (ESRD) has risen in frequency, which may be attributed to improvements in hemodialysis care. Our objective was to describe baseline characteristics and pregnancy outcomes among women with ESRD on hemodialysis.
Methods: Using the United States' Healthcare Cost and Utilization Project-Nationwide Inpatient Sample, we created a cohort of women with ESRD on hemodialysis who gave birth between 2005 and 2015.
Effect of celiac disease on maternal and neonatal outcomes of pregnancy.
J Matern Fetal Neonatal Med
July 2021
Purpose: Celiac disease (CD) is a permanent immune reaction to gluten that is likely related to genetic factors. Some studies have linked CD to adverse maternal and/or neonatal outcomes but the data has been contradictory. The purpose of this study was to evaluate the effect of CD on pregnancy outcomes.
View Article and Find Full Text PDFMaternal and fetal outcomes of urolithiasis: A retrospective cohort study.
J Gynecol Obstet Hum Reprod
November 2021
Article Synopsis
- - The study investigates the incidence of urolithiasis (kidney stones) in pregnant women and compares the outcomes for both mothers and babies affected by this condition.
- - Analyzing data from over 13.7 million pregnant women, the research finds that 11,528 experienced urolithiasis, resulting in an incidence rate of 8.3 per 10,000 pregnancies and an increased risk of complications like preeclampsia, gestational diabetes, and cesarean delivery.
- - The findings suggest that pregnant women with urolithiasis face higher risks for maternal death, congenital anomalies, and premature births, indicating a need for better understanding and management of this condition during pregnancy.