SpO2, heart rate, and arterial blood pressure during successful or failed application of non-invasive ventilation after delivery - a single-centre study.

Introduction: SpO2, heart rate, and systolic, diastolic, and mean arterial blood pressure are among the commonly applied and most frequently chosen indicators of well-being of newborns in intensive care units. Objective: to determine the relationship between the aforementioned parameters and the status of newborns depending on the outcome of the Infant Flow (I-F) therapy, and the development of complications in the form of pneumothorax.

Material And Methods: A retrospective single-centre study covering the years 2009-2014.

Ocular manifestation of congenital toxoplasmosis, clinical implication - case report.

The aim of this case report was to present extremely severe, ophthalmic complications in form of rare, congenital toxoplasmatic bilateral defect of eye-balls concomitant with advanced uveitis, microphthalmia and eye-multistructural developmental abnormalities leading to irreversible visual disability. The ocular diagnosis was confirmed in Ret-Cam II and ultrasonography and it was accompanied with congenital multiorgan lesions including hepato-splenomegaly, thrombocytopenia, leukomalacia, hydrocephalus and ventriculomegaly with neurological symptoms. Serology, PCR of cerebro-spinal fluid and cord blood confirmed the presence of congenital Toxoplasma gondii infection in the infant.

Remifentanil patient-controlled analgesia for labor - monitoring of newborn heart rate, blood pressure and oxygen saturation during the first 24 hours after delivery.

Introduction: There is no available information about the effects of remifentanil labor analgesia on newborns' vital signs in the first hours after delivery. The aim of the study was to assess changes in the heart rate, blood pressure and oxygen saturation during the first 24 h of neonatal life after using remifentanil patient-controlled analgesia (PCA) for labor analgesia.

Material And Methods: Forty-four full-term neonates, 23 from intravenous PCA remifentanil labor anesthesia 0.

School-age spirometry in survivors of chronic lung disease of prematurity in the surfactant era.

Objective: To assess whether school-age spirometry and lung volume outcomes of preterm infants with history of moderate to severe respiratory distress syndrome (RDS), born in the surfactant era and treated with conventional mechanical ventilation (IMV) and discharged home with or without the diagnosis of BPD (chronic lung disease of prematurity), differ from those of term neonates (controls).

Participants: The study included 148 Caucasian school-aged children (38 preterm infants without BPD, 20 preterm infants with BPD and 90 term infants). All infants were born at the Department of Pathology of Pregnancy and Labor, Pomeranian Medical University Szczecin, Poland.

[Congenital epidermolysis bullosa--a case report].

Bullous dermatitis in infants is a clinical term used for a number of disorders associated with primary neonatal pemphigus. The disease requires differentiation of autoimmune disorders such as pemphigus vulgaris, pemphigus foliaceus, and bullous pemphigoid. These diseases are the result of pemphigus IgG antibodies that pass from the mother to the fetus through the placenta.

[Pethidine for labor analgesia; monitoring of newborn heart rate, blood pressure and oxygen saturation during the first 24 hours after the delivery].

Background: There is no information about an effect of pethidine labor analgesia on newborn vital signs in the first hours after the delivery.

Objectives: The aim of the study was to assess changes in heart rate, blood pressure and oxygen saturation during the first 24 hours of life in neonates born after using pethidine for labor analgesia.

Methods: 55 full-term neonates, 34 from intramuscular pethidine labor anesthesia in doses 50-100 mg and 21 born to mothers without any pharmacological form of anesthesia, were studied.

[Meningitis and chosen complications of neonatal period in preterm neonates born to single or multiple pregnancies].

Unlabelled: The aim of this study was to determine the relationship between meningitis and neonatal period of complications such as massive intraventricular hemorrhage and into brain tissue, hypoxic-ischemic white matter injury retinopathy of prematurity 3-5 degrees and deafness in infants born prematurely from single and multiple pregnancies.

Material: The retrospective study covered 460 preterm infants born to single pregnancies and 280 infants born prematurely with multiple pregnancies, hospitalized in the Clinic of Neonatology PUM in the years: 2005-2008.

Results: There were no statistically significant differences between the frequency of occurrence: peri/intraventricular hemorrhages (IVH) III degrees and IV degrees, hypoxic-ischemic injury in white matter, retinopathy of prematurity 3-5 degrees and hearing loss in newborns of both groups.

Two histologically different tumours in a neonate born from an assisted reproductive technology pregnancy.

The first case of a female neonate born from an in vitro fertilization with embryo transfer (IVF-ET) and intracytoplasmic sperm injection (ICSI) (IVF-ET (ICSI) with two histologically different tumours (craniopharyngioma and hepatoblastoma) is described. Anti-neoplasmatic therapy was abandoned due to the significant extent of the disease (craniopharyngioma, 15 x 12 cm in diameter with active internal hydrocephalus; and right liver lobe hepatoblastoma, 5 cm in diameter) and the severely impaired general condition of the neonate. The neonate died on the 30th day of life due to cerebellar and brainstem herniation, followed by circulatory and respiratory failure.

[Maternal active or passive smoking in relation to some neonatal morphological parameters and complications].

Objective: To determine the relationship between maternal active and passive smoking and neonatal morphological parameters, as well as some neonatal complications in full-term newborns.

Methods: 150 women with uncomplicated, singleton pregnancies were assessed by means of a patient questionnaire. Neonates were divided into 3 groups according to obtained information on maternal smoking status--active smoking: n=51, passive smoking: n=49, non-smoking: n=50.

The role of magnetic resonance imaging in early prediction of cerebral palsy.

This work was undertaken to assess the usefulness of magnetic resonance imaging (MRI) of the brain for early prognosis of cerebral palsy. The study group included 47 neonates (24 term and 23 preterm) with symptoms of perinatal asphyxia. MRI examinations in term neonates were performed during the first month of life but not before the second week of life, while in preterm neonates MRI data were acquired between 38 and 40 weeks from conception.

Factors influencing risk of macrosomia in women with gestational diabetes mellitus undergoing intensive diabetic care.

Aims: The aim of study was to assess the impact of intensive diabetic care, defined as target values for fasting glucose of 60-90mg/dl and 1-h postprandial glucose of below 130mg/dl, on neonatal birth weight in relation to risk indicators for fetal macrosomia in women with gestational diabetes mellitus (GDM).

Methods: In women with (N=543) and without GDM (N=1011) age, height, weight, previous GDM, history of macrosomia, family history of type 2 diabetes, parity and weight gain during pregnancy were recorded.

Results: Neonatal birth weight and frequency distribution of macrosomia and infants with small for gestational age did not differ between women with and without GDM.

[Chorioamnionitis in relation to cord blood sICAM-1 and CRP levels of newborns with and without markers of early onset infection].

Unlabelled: THE AIM of the study was an evaluation of the relationship between histological chorioamnionitis and cord blood soluble intercellular adhesion molecule-1 (sICAM-1) and CRP levels.

Material And Methods: in the group of 152 neonates observed for early onset infection (clinical and laboratory signs) the relationship between histological chorioamnionitis and cord blood sICAM-1 (ELISA) and CRP (turbidimetric method) levels was assessed. All these newborns were born in the years 2002-2004 to mothers with risk factors of perinatal infection.

Maternal adipose tissue, maternal and cord blood essential fatty acids and their long-chain polyunsaturated derivatives composition after elective caesarean section.

Background: The essential fatty acids and their long-chain polyunsaturated derivatives (LC PUFAs) are important for the growth and maturation of the fetal organism.

Objective: The aim of a study was to assess the profile of the essential fatty acids and their LC PUFAs in the blood and adipose tissue of pregnant women and in the cord blood after elective caesarean section.

Design: The study group comprised 36 women and 38 their full-term babies born after elective caesarean section.

[Secundum atrial septal defect in newborns of diabetic mothers].

Aim: To evaluate in own material the incidence of secundum atrial septal defect type fossa ovalis (ASD II) with signs of cardio-respiratory maladaptation in infants of diabetic mothers (IDM) during the first 48 hours of life, and subsequent echocardiography follow-up of babies with ASD II during the first year of life.

Material And Methods: In the period from September 2002 to March 2003 a total of 502 neonates were born and 62 number them were from diabetic mothers. Echocardiography scanning was performed in a group of 49 neonates (42 IDM and 7 full-term infants of healthy mothers) with signs of cardio-respiratory maladaptation during the first 48 hours of life.

[Immaturity or hypotrophy? The cord blood leptin levels in preterm and small-for-gestational age neonates].

Objectives: To assess cord blood leptin levels in preterm and small-for-gestational age neonates and determine whether fetal leptin levels correlate with selected clinical parameters associated with prematurity and undernutrition at birth.

Design: Study of preterm newborns (p-AGA; n = 31) and small-for-gestational age (t-SGA; n = 23) cases in a population of neonates born in Szczecin between September 2001 and June 2002.

Methods: Fetal cord blood was sampled after delivery.

[Evaluation of diagnostic usefulness of the cord blood TNF-alpha levels as a marker of early onset neonatal infection].

Objective: The aim of the study was to assess whether cord blood TNF-alpha levels can be useful as a marker of early onset neonatal infection.

Design: A prospective survey of a group of 110 newborns performed during the first 3 days of life.

Methods: The study was performed on a group of 110 newborns.

[Abnormalities in neonatal brain ultrasound examination in relation to cord blood TNF and chorioamnionitis].

The study was undertaken to determine whether PIVH and PVL in neonates are related to cord blood TNF levels and chorioamnionitis. The study material consisted of 54 neonates--31 preterm and 23 full-term. 39 of those babies were born to mothers with clinical signs of intrauterine infection, but only in 20 cases histologic chorioamnionitis were recognised.

Fetal and neonatal arrhythmia in one of the twins--a case history.

There are a lot of publications about fetal arrhythmia in singletons, but up to now there are no published data about fetal arrhythmia in multiple pregnancies. In the present study a case history of fetal and neonatal arrhythmia in one of twins from two mothers treated with betamimetic agents due to imminent preterm labor is reported and discussed. A first case with fetal bradycardia due to complete A-V block had congenital cordis abnormalities (VSD and PFO).

Multiple pregnancy: factors contributing to early infant's breast-feeding--own experience.

The aims of the study were as follows: 1. to evaluate the effectiveness of current program to promote breast-feeding in our population of infants from multiple pregnancy; 2. to define factors responsible for failure in early breast-feeding establishing and/or maintaining breast-feed during the hospitalization of the babies in neonatal department.

[Hypoglycemia in newborn of the diabetic mother in relation to some indicators of perinatal hypoxia].

Design: To examine whether perinatal hypoxia increases the risk of occurrence of hypoglycaemia--between first and second hour of life--in newborn of the diabetic mother.

Material And Methods: The study material consisted of 151 newborns born to 58 pregestational and 93 gestational diabetes mothers. The occurrence of hypoglycaemia was examined in accordance with some perinatal hypoxia indicators such as: 1 and 5 minutes Apgar scores, umbilical arterial blood gas analysis and cord blood erythropoietin (EPO) level.

[Respiratory distress syndrome in newborns of diabetic mothers in the years 1987-1998].

The aim of the study was to estimate which factors contribute to high frequency of RDS in our newborns of the diabetic mothers treated with intensive insulin therapy. The study material consisted of 574 newborns (394 from GDM and 180 from IDDM mothers) born in the years 1987-1998. In the analysed group there were compared: frequency of occurrence of RDS, severity of RDS as well as factors which can contribute to occurrence of RDS.

[Cord blood insulin level in relation to metabolic control of maternal diabetes, duration of pregnancy and neonatal birth weight].

The aim of the study was to examine whether an association between cord blood insulin level (Ic) and maternal glycemic control, duration of pregnancy as well as neonatal birthweight exists. The study was performed in diabetic group consisted of 149 diabetic mothers (91 with GDM and 58 with IDDM) and 149 their babies as well as in the control group consisted of 100 healthy mothers and 100 their babies. Maternal glycemic control was indirectly assessment by using HbA1c and fructosamine levels estimated on the day of delivery.

[Cord blood insulin and erythropoietin levels in relation to the mode of delivery].

Unlabelled: The aim of the study was evaluation, whether cord blood insulin (Ic) and erythropoietin (EPO) levels differ in accordance with mode of delivery: cesarean section (CS) or vaginal delivery (VD).

Material And Methods: The study was performed in the diabetic group consisted of 148 newborns of diabetic mothers (NDM)--90 of them with GDM and 58 with IDDM as well as in the control group consisted of 100 newborns born to healthy mothers. 52.

[Cord blood erythropoietin in relation to glycemic control in the last weeks of pregnancy].

The relationship between cord blood erythropoietin (EPO) and maternal HbA1c and fructosamine levels were examined in the aim to answer a question, whether occurrence of prenatal hypoxia in newborns of diabetic mothers depends from maternal glycemic control during the last weeks of pregnancy. The study was performed in the group of 178 mothers and newborns divided into two groups: diabetic and control. The diabetic group consisted of 116 mothers (33 with IDDM and 83 with GDM) and newborns and the control group consisted of 62 healthy mothers and newborns.

[Estimated levels of fructosamine in venous blood of pregnant women and in cord blood].

In the study there was estimated maternal (Fm) and cord blood (Fc) fructosamine levels in 151 diabetic (58 PGDM and 93 GDM) and 100 control subjects on the day of delivery. It was found that Fm and Fc levels in PGDM and GDM groups were significantly higher than in the control group. It was also found the significantly positive correlation between Fm and Fc levels in all study groups.