Developing a coaching manual to provide human support for the Mothers and Babies Online (eMB) perinatal mental health intervention.

Background: Depression that occurs in pregnancy or postpartum (perinatal depression) impacts 1 in 5 mothers, yet access to effective and high-quality preventative interventions remains elusive for most. Digital interventions are a promising solution to this treatment gap because of the ubiquity of mobile devices and internet access. The Mothers and Babies Online Course (eMB) is an online adaptation of Mothers and Babies, an evidence-based preventative program for postpartum depression.

Stiffness of Experimentally Tested Horizontally Loaded Walls and Timber-Framed Modular Building.

This paper presents an overview of representative up-to-date research and the authors' own experimental results from tests of wall elements and a horizontally loaded timber-framed modular building. The research has been conducted in connection with the development of timber-based structures in recent years. In the present research, wall elements and modules of timber-frame construction with life-size dimensions were used.

COVID-19 resilience index in European Union countries based on their risk and readiness scale.

Addressing risks and pandemics at a country level is a complex task that requires transdisciplinary approaches. The paper aims to identify groups of the European Union countries characterized by a similar COVID-19 Resilience Index (CRI). Developed in the paper CRI index reflects the countries' COVID-19 risk and their readiness for a crisis situation, including a pandemic.

Phytochemical Profiling, Antioxidant and Tyrosinase Regulatory Activities of Extracts from Herb, Leaf and In Vitro Culture of (Yarrow).

L. is one of the most known medicinal plants with a broad spectrum of applications in the treatment of inflammation, pain, microbial infections and gastrointestinal disorders. In recent years, the extracts from have also been applied in cosmetics with cleansing, moisturizing, shooting, conditioning and skin-lightening properties.

Cannabidiol and Minor Phytocannabinoids: A Preliminary Study to Assess Their Anti-Melanoma, Anti-Melanogenic, and Anti-Tyrosinase Properties.

Currently, there is an increased interest from both scientists and consumers in the application of cannabis/hemp/phytocannabinoids in skin-related disorders. However, most previous investigations assessed the pharmacological properties of hemp extracts, cannabidiol (CBD), or tetrahydrocannabinol (THC), with very few studies focusing on minor phytocannabinoids from hemp. In this context, the current work explored the anti-melanoma, anti-melanogenic, and anti-tyrosinase effects of cannabidiol (CBD) and three minor phytocannabinoids, namely cannabigerol (CBG), cannabinol (CBN), and cannabichromene (CBC).

Experimental Studies and Numerical Simulations of FRP Poles Failure in the Area of Inspection Hole.

Glass fiber-reinforced polymer (GFRP) utility poles are becoming more widespread in European countries. To ensure the integrity and safety of poles, it is necessary to carefully examine their structural features. The purpose of this paper is to present the numerical model of a column made with the engineering simulation software ANSYS and to compare the experimentally determined values of the stresses that lead to column failure close to the inspection hole with the results obtained using the numerical model.

Extracts from European Propolises as Potent Tyrosinase Inhibitors.

Tyrosinase is a key enzyme in the melanogenesis pathway. Melanin, the product of this process, is the main pigment of the human skin and a major protection factor against harmful ultraviolet radiation (UVR). Increased melanin synthesis due to tyrosinase hyperactivity can cause hyperpigmentation disorders, which in consequence causes freckles, age spots, melasma, or postinflammatory hyperpigmentation.

Multidirectional Characterization of Phytochemical Profile and Health-Promoting Effects of Juz. Extracts.

species (Lamiaceae) have been used in traditional medicine as sedatives, antiseptics, carminatives, or expectorants. Despite their common applications in phytotherapy, there is still lack of evidence about the composition of their extracts and its impact on biological properties of the plants. The aim of this study was to evaluate the content of , a less studied species growing in Kazakhstan, using HPLC-ESI-QTOF-MS/MS instrumentation and to determine its antimicrobial, antioxidant, and cytotoxic activity together with inhibitory properties against tyrosinase and toxicity in erythrocyte lysis assay.

Assessment of spp. Peel Extracts as Potential Sources of Active Substances for Skin Care and Dermatology.

By-products of cultivated plants are one of the major environmental concerns worldwide. Due to the high concentration of bioactive chemicals, such waste may be considered hazardous due to the interference with the plant growth, deterioration of the drinking water quality or toxic effects on sensitive marine organisms. Moreover, plant-derived by-products, with proper handling, may represent a low-cost source of bioactive compounds potentially important for pharmaceutical and cosmetics industries.

Investigation of the Dynamic Stiffness of Poroelastic and Asphalt Concrete Layers under In Situ and Laboratory Conditions.

Compounds with lower dynamic stiffness are a better solution from the tyre/road noise point of view. The article presents the constructed test stand for the evaluation of dynamic stiffness both in in situ and in laboratory conditions. As a result of the tests, it was found that poroelastic pavements have a much lower dynamic stiffness (from 138.

Rationale and usability findings of an e-health intervention to improve oral anticancer adherence among breast cancer survivors: The My Journey mindfulness study.

Background: Approximately 80% of breast cancer survivors are prescribed oral endocrine therapy (ET) medication for 5-10 years following primary treatment, making adherence to ET a critical aspect of cancer survivorship care. Despite the benefits of ET, non-adherence is problematic, and up to half of breast cancer survivors ave been documented to discontinue ET early. Our team developed , an online, mindfulness-based program designed to improve adherence to ET.

Insights into the Phytochemical and Multifunctional Biological Profile of Spices from the Genus .

spices represent an inexhaustible reservoir of bioactive compounds that may act as drug leads in natural product research. The aim of this study was to investigate a series of methanolic fruit extracts obtained from (black, green, white and red), and in comparative phytochemical and multi-directional biological (antimicrobial, antioxidant, anti-enzymatic and anti-melanogenic) assays. The metabolite profiling revealed the presence of 17 piperamides, with a total content of 247.

The Phenolic Compounds Profile and Cosmeceutical Significance of Two Kazakh Species of Onions: and .

Numerous species of genus have been used in the traditional medicine based on their vast biological effects, e.g., antimicrobial, digestion stimulant, anti-sclerotic, soothing, antiradical or wound healing properties.

Hybrid Polymer Composites Used in the Arms Industry: A Review.

Polymer fiber composites are increasingly being used in many industries, including the defense industry. However, for protective applications, in addition to high specific strength and stiffness, polymer composites are also required to have a high energy absorption capacity. To improve the performance of fiber-reinforced composites, many researchers have modified them using multiple methods, such as the introduction of nanofillers into the polymer matrix, the modification of fibers with nanofillers, the impregnation of fabrics using a shear thickening fluid (STF) or a shear thickening gel (STG), or a combination of these techniques.

Dynamic Stiffness of Bituminous Mixtures for the Wearing Course of the Road Pavement-A Proposed Method of Measurement.

Stiffness is an important mechanical characteristic of asphalt mixtures used in the wearing course. It is one of the determining factors in the generation of tyre/road noise. The dynamic stiffness of the upper layer of the road surface depends on the physical and mechanical properties of the materials it is composed of, and traffic load.

Communication: Multidimensional triple sum-frequency spectroscopy of MoS and comparisons with absorption and second harmonic generation spectroscopies.

Triple sum-frequency (TSF) spectroscopy is a recently developed methodology that enables collection of multidimensional spectra by resonantly exciting multiple quantum coherences of vibrational and electronic states. This work reports the first application of TSF to the electronic states of semiconductors. Two independently tunable ultrafast pulses excite the A, B, and C features of a MoS thin film.

Visualization and Studies of Ion-Diffusion Kinetics in Cesium Lead Bromide Perovskite Nanowires.

The facile chemical transformation of metal halide perovskites via ion exchange has been attributed to their "soft" crystal lattices that enable fast ion migration. Kinetic studies of such processes could provide mechanistic insights on the ion migration dynamics. Herein, by using aligned single-crystal nanowires of cesium lead bromide (CsPbBr) perovskite on epitaxial substrates as platforms, we visualize and investigate the cation or anion interdiffusion kinetics via spatially resolved photoluminescence measurement on heterostructures fabricated by stacking CsPbCl, MAPbI, or MAPbBr microplates on top of CsPbBr nanowires.

Single-Crystal Thin Films of Cesium Lead Bromide Perovskite Epitaxially Grown on Metal Oxide Perovskite (SrTiO).

High-quality metal halide perovskite single crystals have low defect densities and excellent photophysical properties, yet thin films are the most sought after material geometry for optoelectronic devices. Perovskite single-crystal thin films (SCTFs) would be highly desirable for high-performance devices, but their growth remains challenging, particularly for inorganic metal halide perovskites. Herein, we report the facile vapor-phase epitaxial growth of cesium lead bromide perovskite (CsPbBr) continuous SCTFs with controllable micrometer thickness, as well as nanoplate arrays, on traditional oxide perovskite SrTiO(100) substrates.

Basal-Plane Ligand Functionalization on Semiconducting 2H-MoS Monolayers.

Molybdenum disulfide (MoS) is a two-dimensional material promising for electronic, optical, and catalytic applications. To fully harness its potential, functionalization is essential to controlling its properties. However, MoS functionalization has been mostly limited to either 1T-phase MoS or the edges of 2H-phase MoS, and the chemistry of covalent functionalization on the basal plane of 2H-MoS is poorly understood.

Atypical Plasmacytic Proliferation in a Case of C3 Glomerulopathy: Pathophysiology Demystified.

An 11-year-old Hispanic female underwent evaluation of asymptomatic proteinuria and hematuria. The patient denied fever, edema, and gross hematuria. Urinalysis showed mild proteinuria, and a urine microscopic examination revealed red blood cells.

Approach to Pediatric Patients with UTI in the PICU.

Urosepsis and UTI are common causes and comorbidities in children admitted to the pediatric intensive care unit (PICU). Risk factors for morbidity and mortality in pediatric patients include young age (< 2 years old), presence of congenital renal anomalies of the urinary tract, and immunosuppression from transplant (kidney, liver, heart, and bone marrow). Workup of urosepsis focuses on identification of renal anomalies of the urinary tract through ultrasound, X-ray cystourethrogram, urodynamic studies, and CT/MRI.

A 13-Month-Old With Xanthogranulomatous Pyelonephritis With Features of Renal Malakoplakia.

Xanthogranulomatous pyelonephritis is an uncommon chronic inflammatory renal disorder caused by chronic infection with gram-negative bacteria leading to destruction of the renal parenchyma and replacement with foamy lipid-laden macrophages. Renal malakoplakia is another rare form of chronic inflammatory granulomatous disease in the kidney associated with infection usually occurring in adults with immunocompromised status or debilitating disease. It is hallmarked by the finding of foamy histiocytes with distinctive basophilic inclusions (Michaelis-Gutmann bodies).