Publications by authors named "Cyrus Safaeipour"
Article Synopsis
- PRMT7 and PRMT9 are emerging as important therapeutic targets, but their biological functions and structural requirements for selective inhibitors are not well-understood.
- Recent research identified a potent inhibitor for both PRMT7 and PRMT9 and investigated its binding mechanism to these proteins.
- Label-free quantification mass spectrometry demonstrated significant inhibition of PRMT activity in cells, and an AlphaLISA assay was developed for screening PRMT9 inhibitors.
