Publications by authors named "Cyrrene Sharples"
Article Synopsis
- This study reveals that macrophage migration inhibitory factor (MIF) is crucial for early nerve growth in the inner ear of mice and chicks.
- MIF, released by the developing otocyst, promotes the outgrowth and survival of neurons from the statoacoustic ganglion and is found in both developing and adult inner ear tissues.
- Knockout mice lacking MIF show hearing impairment and abnormal nerve connections, emphasizing MIF's significant role in neural development.
Background: Fecal occult blood testing (FOBT) is one method to screen for colorectal cancer and to assess for gastrointestinal bleeding in hospitalized patients. Differences in the analytical sensitivity among various methods may have significant clinical repercussions.
Methods: We evaluated the analytical performance of 5 different FOBT methods (standard guaiac-based method and four immunochemical methods) using patient samples and spiked stool specimens.