Publications by authors named "Cyrille Leonel Tchuente Djoko"
3,3'4-trimethoxy-4'-rutinosylellagic acid and its acetylated derivative: Antioxidant activity and antiproliferative effects on breast cancer cells and molecular docking study.
Romeo Toko Feunaing Alfred Ngenge Tamfu Abel Joel Yaya Gbaweng Cyrille Leonel Tchuente Djoko Fidele Ntchapda
Biomed Pharmacother
October 2024
Article Synopsis
- - The study investigates two natural compounds, TR2 and TR22, for their potential antioxidant and anticancer properties against two types of breast cancer cells (estrogen-sensitive MCF-7 and non-sensitive MDA-MB 231).
- - TR2 demonstrated stronger antioxidant effects compared to standard antioxidants and effectively inhibited the growth and migration of breast cancer cells, while TR22 showed a more significant proliferation inhibition following acetylation.
- - Molecular docking studies indicated that both compounds could inhibit receptor tyrosine kinases, suggesting their potential as effective agents in slowing cancer progression.