Scintillation in Liquid Xenon for Gamma-Ray Medical Imaging: From Single Time-over-Threshold to Multi-Time-over-Threshold PMT Signal Measurements.

In this paper, a new light event acquisition chain in a three-gamma liquid xenon prototype for medical nuclear imaging is presented. The prototype implements the Multi-Time-Over-Threshold (MTOT) method. This method surpasses the Single-Time-Over-Threshold (STOT) by precisely determining both the number of vacuum ultraviolet (VUV) photons detected by each photomultiplier tube (PMT) and their arrival times for light signal measurement.

Design of a Multimodal Oculometric Sensor Contact Lens.

Oculometric data, such as gaze direction, pupil size and accommodative change, play a key role nowadays in the analysis of cognitive load and attentional activities, in particular with the development of Integrated Visual Augmentation Systems in many application domains, such as health, defense and industry. Such measurements are most frequently obtained by different devices, most of them requiring steady eye and body positions and controlled lighting conditions. Recent advances in smart contact lens (SCL) technology have demonstrated the ability to achieve highly reliable and accurate measurements, preserving user mobility, for instance in measuring gaze direction.

Multipurpose Bio-Monitored Integrated Circuit in a Contact Lens Eye-Tracker.

We present the design, fabrication, and test of a multipurpose integrated circuit (Application Specific Integrated Circuit) in AMS 0.35 µm Complementary Metal Oxide Semiconductor technology. This circuit is embedded in a scleral contact lens, combined with photodiodes enabling the gaze direction detection when illuminated and wirelessly powered by an eyewear.

Development of a new scleral contact lens with encapsulated photodetectors for eye tracking.

Most eye trackers nowadays are video-based, which allows for a relatively simple and non-invasive approach but also imposes several constraints in terms of necessary computing power and conditions of use (e.g., lighting, spectacles, etc.

Flexible Micro-Battery for Powering Smart Contact Lens.

In this paper, we demonstrate the first attempt of encapsulating a flexible micro battery into a contact lens to implement an eye-tracker. The paper discusses how to scale the battery to power various circuits embedded in the contact lens, such as ASIC, photodiodes, etc., as well as how to combine the battery with external harvested energy sources.

A sub-nJ CMOS ECG classifier for wireless smart sensor.

Body area sensor networks hold the promise of more efficient and cheaper medical care services through the constant monitoring of physiological markers such as heart beats. Continuously transmitting the electrocardiogram (ECG) signal requires most of the wireless ECG sensor energy budget. This paper presents the analog implantation of a classifier for ECG signals that can be embedded onto a sensor.

Ligament imbalance metrics and an autonomous measurement system for post TKA.

This paper describes two useful metrics to estimate the ligament imbalance for post Total Knee Arthroplasty (TKA) scenario: the center of pressure and the net moments (varus-valgus and anterior posterior). Both metrics have been evaluated using high level models and experimental measurement. Self-powered analog and digital architectures for the center of pressure are elaborated here and complies with the Medical Implant Communication Service (MICS) standard.

A self-powered telemetry system to estimate the postoperative instability of a knee implant.

Estimating in vivo the life span of a total knee replacement prosthesis is currently done by estimating the polyethylene (PE) wear rate from measurement of the femorotibial distance using X-ray photographies. This efficient method requires, however, waiting for few years to obtain a readout. This letter proposes using another metric that can be obtained within a couple of months of surgery, namely the center of pressure (COP).