Publications by authors named "Cyril Guillier"

Unlabelled: The short-term respiratory consequences of small for gestational (SGA) are only partially known. Our aim was to compare the early respiratory features between SGA and appropriate for gestational age (AGA) in very preterm infants. We conducted a secondary analysis of the French prospective EPIPAGE-2 cohort.

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Article Synopsis
  • Systematic cultures of central line tips in NICUs may not be as clinically useful due to high bacterial contamination rates during removal, leading to debate on their necessity.
  • A retrospective study analyzed infections and bacterial colonization in 375 newborns with central catheters, finding a 43% colonization rate and 31 confirmed catheter-related infections among suspected sepsis cases.
  • The study suggests that only culturing catheters when infections are suspected could be a more efficient approach than routine screening, as antibiotic effectiveness did not significantly differ between expert recommendations and actual prescriptions.
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Intrauterine growth restriction (IUGR) increases the risk of bronchopulmonary dysplasia (BPD), one of the major complications of prematurity. Antenatal low-protein diet (LPD) exposure in rats induces IUGR and mimics BPD-related alveolarization disorders. Peroxisome proliferator-activated receptor-γ (PPARγ) plays a key role in normal lung development and was found deregulated following LPD exposure.

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To evaluate the efficacy and safety of remifentanil as a premedication in neonates undergoing elective intubation. This retrospective study focused on neonates admitted to the Neonatal Intensive Care Unit of Port-Royal, Paris Centre University Hospitals, France, between June 2016 and November 2017, who received remifentanil before an elective intubation. First, atropine (10 μg/kg) was administered intravenously as a bolus, followed by remifentanil, which was administrated continuously.

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