Publications by authors named "Cyril Gella"
Article Synopsis
- Classical BCR-ABL-negative myeloproliferative neoplasms (MPNs) are disorders caused by mutations in specific genes, primarily affecting hematopoietic stem cells.
- Interferon α (IFNα) has shown potential in inducing remission for MPN patients, and a study involving 48 patients over 5 years assessed its long-term effectiveness by analyzing cell mutations.
- Findings suggest that IFNα is more effective in treating homozygous JAK2V617F mutations and that molecular responses vary with different mutations and dosages of IFNα, indicating a mechanism of HSC exhaustion.
