Publications by authors named "Cynthia Santos"

Watermelon (), it's an important fruit in Brazil, producing 1.9 million ton/year, occupies the fifth place in the world, (FAO, 2022), but post-harvest diseases are a major limitation, leading to losses of up to 15% (Balasubramaniam et al. 2023).

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Article Synopsis
  • Buprenorphine is typically given sublingually for opioid withdrawal, but when that's not possible, intravenous (IV) or intramuscular (IM) methods can be effective alternatives despite limited practitioner experience in this area.
  • A case series reviewed patient charts from an urban hospital who received parenteral buprenorphine between January 2020 and December 2021, focusing on demographics, medical and substance use histories, and withdrawal outcomes.
  • Out of eight patients studied, the majority responded positively to the treatment, showing improvement in withdrawal symptoms, especially in cases with issues like delirium; no adverse effects were reported, indicating promise for this method in future applications.
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Background: Safety design covers proactive actions as it analyzes accident risks early in the enterprise life cycle, and considers the designer acting on accident prevention as a member of the construction team.

Objective: This paper proposes an accident investigation to establish links between accident causes and design to support Prevention through Design (PtD) tools.

Methods: This article analyzed more than a thousand severe and fatal accident cases in the construction sector.

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Objective: To evaluate the relationship between vitamin D status and hypertriglyceridemic-waist (HTW) phenotype and cardiometabolic markers in individuals with type 2 diabetes mellitus (T2DM) living in regions with high solar incidence (10° south).

Methods: An observational, cross-sectional study, with 122 individuals with T2DM, of both sexes, aged between 19 and 59 years, residing in Sergipe/Brazil. Measurements included serum 25-hydroxyvitamin D (25[OH]D), glucose, insulin, total cholesterol, LDL-c, HDL-c, triacylglycerols, blood pressure, body mass index, %body fat, and waist circumference.

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Menopause and vitamin D deficiency increase bone reabsorption and bone fracture risk in women in postmenopause, and vitamin D supplementation may improve bone health and decrease bone fracture risk. This study aims to discuss the effect of vitamin D supplementation, isolated or calcium-associated, on remodeling and fracture risk bone in women in postmenopause without osteoporosis. This study was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PROSPERO database registration: CRD42022359796).

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Background: Prevention through Design (PtD) is a safety initiative that increases the ability of eliminating risks before construction. Implementing digital tools for PtD is an innovative way to help identify embedded risk in design phase by automating a process that is currently time consuming and extensively dependent on designers' experience. However, there is a lack of known digital safety tools available to professionals.

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Introduction: Emergency Department Peer Navigator Programs (EDPN) have been shown to increase the prescribing of medications for opioid use disorder (MOUD) and improve linkage to addiction care. However, what is not known is whether it can improve overall clinical outcomes and healthcare utilization in patients with OUD.

Methods: This is a single-center, IRB approved, retrospective cohort study using patients with OUD enrolled in our peer navigator program from 11/7/19 to 2/16/21.

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Hypomagnesemia and unhealthy eating patterns are associated with poor glycemic control in individuals with type 2 diabetes mellitus (T2DM). This study aimed to associate magnesium status and dietary patterns with glycemic control in T2DM individuals. This cross-sectional study included 147 individuals with T2DM, aged between 19 and 59 years, of both sexes, residents in Sergipe/Brazil.

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In recent years many emergency departments (EDs) have adopted interventions to help patients with opioid use disorder (OUD), particularly buprenorphine initiation and ED-based peer recovery support. There are limited data on the impact of peer navigators on provider naloxone kit distribution and buprenorphine utilization. We aimed to examine the impact of a peer recovery program on naloxone kit distribution and buprenorphine administration.

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Triptans are potent serotoninergic vasoconstrictors. They are generally avoided in elderly patients age greater than 65 or in patients with a history of CAD. Although there are reported cases of Acute Coronary Syndrome (ACS) or Transient Global Amnesia (TGA) in patients after ingesting therapeutic doses of triptan or dihydroergotamine, this is the first case report, up to our knowledge, of a patient, who had no previous cardiac history, that was diagnosed with both ACS and TGA.

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Context: Foods containing vitamin D reduce the deficiency of this vitamin and improve bone turnover.

Objective: To discuss effects of the intake of vitamin D-fortified foods in isolated form or associated with calcium on bone remodeling in postmenopausal women.

Data Sources: PubMed, Lilacs, Scopus, and Bireme databases.

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Aims: Although excessive fat and caffeine intake are independent risk factors for bone microstructural and functional disturbances, their association remains overlooked. Thus, we investigated the impact of high-fat diet (HFD) and caffeine alone and combined on serum lipid profile, bone microstructure, micromineral distribution and biomechanical properties.

Methods: Forty female C57BL/6 mice were randomized into 4 groups daily treated for seventeen weeks with standard diet (SD) or HFD (cafeteria diet) alone or combined with 50 mg/kg caffeine.

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Buprenorphine is an effective treatment for opioid dependence; however, it demonstrates individual variability in efficacy. Pharmacogenomics may explain this drug response variability and could allow for tailored therapy on an individual basis. The Food and Drug Administration and the Clinical Pharmacogenomics Implementation Consortium have guidelines on pharmacogenomic testing for some opioids (e.

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To examine the effectiveness of four doses of psychostimulant medication, combining extended-release methylphenidate (ER-MPH) in the morning with immediate-release MPH (IR-MPH) in the afternoon, on cognitive task performance. The sample comprised 24 children (19 boys and 5 girls) who met the (DSM-IV-TR) criteria for an autism spectrum disorder (ASD) on the and the , and had significant symptoms of attention-deficit/hyperactivity disorder (ADHD). This sample consisted of elementary school-age, community-based children (mean chronological age = 8.

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Article Synopsis
  • Flecainide is a medication for treating heart rhythm disturbances but has serious side effects, including cardiac arrest and heart failure, which can complicate its diagnosis, particularly in the emergency department.
  • A case study highlighted a 58-year-old woman with altered mental status and hypoxia due to sepsis, revealing that her wide complex tachycardia was caused by flecainide toxicity related to acute kidney injury.
  • Emergency physicians should be aware of flecainide toxicity, as timely diagnosis and treatment can prevent life-threatening complications, especially since serum levels can take several days to determine.
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Introduction: Worldwide an estimated one million deaths occur annually as a result of poisoning. Internationally there is a lack of toxicology training programs, especially in resource poor settings. We developed a one-day, interactive toxicology curriculum for healthcare practitioners in countries lacking clinical toxicology training and evaluated its feasibility and effectiveness for knowledge dissemination.

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Background: The Global Terrorism Database (GTD) is an open-source database on terrorist incidents around the world since 1970, and it is maintained by the National Consortium for the Study of Terrorism and Responses to Terrorism (START; College Park, Maryland USA), a US Department of Homeland Security Center of Excellence. The consortium reviews media reports to determine if an event meets eligibility to be categorized as a terrorism incident for entry into the database.

Objective: The objective of this study was to characterize chemical terrorism incidents reported to the GTD and understand more about the kinds of chemical agents used, the associated morbidity and mortality, the geography of incidents, and the intended targets.

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Bismuth subsalicylate (BSS) is the active ingredient in over-the-counter antacid and antidiarrheal medications. Coagulopathy in the setting of acetylsalicylic acid toxicity is well documented but not in setting of bismuth subsalicylate overuse. We present a case report of coagulopathy from BSS poisoning in a patient with underlying cirrhosis.

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