The objective of this study is to evaluate the association between quality and features related to internet users of the most viewed YouTube videos about COVID-19 and chloroquine, during the first wave of the pandemic. We conducted a cross-sectional observational study focusing on the most viewed YouTube videos on COVID-19 and chloroquine treatment, in French and English. The primary outcome was the association between video quality as assessed by DISCERN and modified JAMA scores, and video features related to internet users as assessed by number of viewership and likes.
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