Publications by authors named "Cynthia Layse Ferreira de Almeida"
Article Synopsis
- The study explored the antiulcer effects of an ethanolic extract (SmEE) from a plant, as well as its main components, gallic acid (GA) and ellagic acid (EA), which are known for their medicinal properties.
- Various assays were conducted to determine the extract's antioxidant activity, revealing SmEE's ability to significantly reduce ulcer size in models induced by ethanol and non-steroidal anti-inflammatory drugs (NSAIDs).
- The findings indicate that not only does SmEE have protective effects on the gastric mucosa, but GA and EA also work together synergistically to enhance this protection against ulcers.
Phenolic compounds, among them isopropyl caffeate, possess antioxidant potential, but not without toxicity and/or adverse effects. The present study aimed to evaluate the antioxidant activity and toxicity of isopropyl caffeate through in silico, and testing. The results showed that isopropyl caffeate presents no significant theoretical risk of toxicity, with likely moderate bioactivity: GPCR binding, ion channel modulation, nuclear receptor binding, and enzyme inhibition.
View Article and Find Full Text PDFis used in folk medicine to treat diarrhea and diuresis. The objective of this study was to evaluate the phytochemical profile and antioxidant and antiulcer activities of the hexane extract of the leaves of (SpHE). Phytochemical profile was evaluated via thin layer chromatography (TLC) and HPLC.
View Article and Find Full Text PDFInflammation is a complex event linked to tissue damage whether by bacteria, physical trauma, chemical, heat or any other phenomenon. This physiological response is coordinated largely by a variety of chemical mediators that are released from the epithelium, the immunocytes and nerves of the lamina propria. However, if the factor that triggers the inflammation persists, the inflammation can become relentless, leading to an intensification of the lesion.
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