Publications by authors named "Cynthia Grandjean"

Between 2002 and 2012, the number of individuals > 55 years of age in the workforce is projected to climb by approximately 50%. Few studies have substantiated that severe occupational injury to older workers is a significant problem. To identify the variables related to traumatic injuries of older workers, data were abstracted retrospectively from a regional trauma center database, including demographic and injury characteristics, length of hospital and intensive care unit (ICU) stay, and cost.

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While tissue-type plasminogen activator (tPA) is currently the standard "clot-busting" drug used to treat patients with acute ischemic stroke, another new option for treatment is now under clinical study. Desmodus rotundus plasminogen activator (DSPA), an enzyme found in the saliva of vampire bats, may offer another therapeutic option instead of tPA, a current therapy for stroke. Animal research indicates that tPA may mediate neuronal death as well as increase systemic plasminogen consumption and fibrinogenolysis.

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