Draft genome sequences of four strains, SC302, SC304, SC306, and SC310, isolated from swine from Eastern Canada.

The bacterium causes porcine exudative epidermitis in piglets, which represents both health and welfare concerns. Few genome sequences of this pathogen are published. We provide four additional ones to help future genomic analysis of .

isolates from Canada demonstrate wide distribution and clustering among mesophilic strains.

All the 36 known species to date of the genus are mesophilic except the species , which includes both psychrophilic and mesophilic subspecies. For 20 years, more and more mesophilic strains have been discovered. Only subsp.

Asymmetrical dose responses shape the evolutionary trade-off between antifungal resistance and nutrient use.

Antimicrobial resistance is an emerging threat for public health. The success of resistance mutations depends on the trade-off between the benefits and costs they incur. This trade-off is largely unknown and uncharacterized for antifungals.

Various dictyostelids from the environment can produce multilamellar bodies.

Multilamellar bodies (MLBs), structures composed of concentric membrane layers, are known to be produced by different protozoa, including species of ciliates, free-living amoebae, and social amoebae. Initially believed to be metabolic waste, potential roles like cell communication and food storage have been suggested for MLBs, which could be useful for the multicellular development of social amoebae and as a food source. However, among dictyostelids, this phenomenon has only been observed with , and mainly with laboratory strains grown in axenic conditions.

Structural insights into the putative bacterial acetylcholinesterase ChoE and its substrate inhibition mechanism.

Mammalian acetylcholinesterase (AChE) is well-studied, being important in both cholinergic brain synapses and the peripheral nervous systems and also a key drug target for many diseases. In contrast, little is known about the structures and molecular mechanism of prokaryotic acetylcholinesterases. We report here the structural and biochemical characterization of ChoE, a putative bacterial acetylcholinesterase from Analysis of WT and mutant strains indicated that ChoE is indispensable for growth with acetylcholine as the sole carbon and nitrogen source.

Draft Genome Sequences of Four Aeromonas salmonicida subsp. achromogenes Strains, 23051, 23053, 23055, and 23056, Isolated from Senegalese Sole ().

The bacterial species officially has five subspecies. A large majority of the currently available sequences come from subsp. , which causes furunculosis in salmonids.

A new approach to study attached biofilms and floating communities from Pseudomonas aeruginosa strains of various origins reveals diverse effects of divalent ions.

Pseudomonas aeruginosa is an opportunistic pathogen associated with nosocomial infections and disease complications. In the lungs of cystic fibrosis (CF) individuals, biofilm growth plays a crucial role in the persistence and antibiotic resistance of P. aeruginosa.

A multi-host approach to identify a transposon mutant of Pseudomonas aeruginosa LESB58 lacking full virulence.

Objective: Pseudomonas aeruginosa is an opportunistic bacterial pathogen well known to cause chronic lung infections in individuals with cystic fibrosis (CF). Some strains adapted to this particular niche show distinct phenotypes, such as biofilm hyperproduction. It is necessary to study CF clinical P.

Increasing genomic diversity and evidence of constrained lifestyle evolution due to insertion sequences in Aeromonas salmonicida.

Background: Aeromonads make up a group of Gram-negative bacteria that includes human and fish pathogens. The Aeromonas salmonicida species has the peculiarity of including five known subspecies. However, few studies of the genomes of A.