Publications by authors named "Cynthia Cockerham"
Objectives: Food insecurity (FI) may be associated with worsened neonatal abstinence syndrome severity in infants born to individuals with substance use disorder. This study evaluates FI and housing insecurity (HI) influence on maternal and neonatal outcomes.
Methods: This was a cohort study of patients receiving obstetric care through a multispecialty program in Kentucky from 2015 to 2023.
Objective: Evaluate maternal and neonatal outcomes after buprenorphine wean compared to patients maintained on buprenorphine throughout pregnancy.
Methods: Prospective cohort study of pregnant patients with opioid use disorder enrolled in a multidisciplinary treatment program between 2015 and 2022. All patients were offered Medications to treat Opioid Use Disorder (MOUD) primarily with buprenorphine.
Emerging evidence indicates a previously unrecognized, clinically relevant spectrum of abnormal aldosterone secretion associated with hypertension severity. It is not known whether excess aldosterone secretion contributes to hypertension during pregnancy. We quantified aldosterone concentrations and angiotensin peptides in serum (using liquid chromatography with tandem mass spectrometry) in a cohort of 128 pregnant women recruited from a high-risk obstetrics clinic and followed prospectively for the development of gestational hypertension, pre-eclampsia, superimposed pre-eclampsia, chronic hypertension, or remaining normotensive.
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- * A study examined the renin-angiotensin-aldosterone system (RAAS) in 74 pregnant women to compare those who experienced gestational hypertension (HYP) with those who remained normotensive (NT).
- * The findings revealed that while NT pregnancies showed an increase in key RAAS components throughout pregnancy, HYP cases retained low levels of these components, particularly in the third trimester, indicating a malfunction in the RAAS during hypertensive pregnancies.