Sleep Sci
January 2022
Introduction: Chronic pain, nocturnal cramps, and sleep alterations are prevalent symptoms and signals in Charcot-Marie-Tooth disease patients. Sleep and pain are bidirectionally related and physical therapy can improve the binomial sleep and pain/nocturnal cramps. Therefore, we hypothesized that the application of a specific physical therapy program for Charcot-Marie-Tooth disease would improve sleep quality, pain perception, and nocturnal cramps.
View Article and Find Full Text PDFSleep Sci
January 2022
Introduction: Charcot-Marie-Tooth disease is an inherited neuropathy that presents two main forms - type 1 and type 2 -, differentiated by the speed of the nervous conduction. Our goal was to assess sleep in Charcot-Marie-Tooth disease and its relationship with pain perception and nocturnal cramps.
Material And Methods: This was a case-control study.
Gait Posture
May 2018
Background: Charcot-Marie-Tooth (CMT) disease is part of a group of genetically determined neuropathies. The intrinsic muscles of the feet and legs are affected early in the disease, impacting balance and mobility.
Research Question: The purpose of this study was to evaluate individuals with type 2 Charcot-Marie-Tooth disease to understand how motor changes interfere in balance and function.
Eur Neurol
August 2016
The aim of this study was to evaluate the pulmonary condition in a large family with Charcot-Marie-Tooth disease type 2 (CMT2). Eighteen participants diagnosed with CMT2 and 20 healthy individuals were evaluated by spirometry and maximal expiratory and maximal inspiratory pressures (MEP and MIP, respectively). Clinical disability was measured with CMT neuropathy score (CMTNS; range 0-36).
View Article and Find Full Text PDFPurpose: To evaluate the effect of different application frequencies of dentifrices containing CPP-ACP and fluoride on enamel demineralization inhibition using a pH cycling model.
Methods: A total of 120 enamel blocks obtained from permanent human third molars were divided into eight groups according to the treatment and number of times that the dentifrice slurry was applied (three or five times): Control--Dentifrice without Fluoride (CO3 and CO5); Fluoride Dentifrice (FD3 and FD5--commercial dentifrice 1100 ppm as NaF); MI Paste (MP3 and MP5--Recaldent) and MI Paste Plus (MPP3 and MPP5--Recaldent 900 ppm as NaF). The specimens were alternately soaked in a demineralizing solution for 6 hours and in a remineralizing solution for 18 hours for 5 days.
Objectives: Charcot-Marie-Tooth (CMT) disease is the most prevalent hereditary motor and sensory polyneuropathy, and a condition in which sleep has rarely been studied, particularly in relation to the type 2 (CMT2). Thus, we aimed to characterize the sleep patterns of a family affected by CMT2 disease.
Methods: Sixteen volunteers with CMT2 from the same multigenerational family agreed to participate in the study (refusal rate = 31%).
Background: The aim of this study was to evaluate the oral health status of temporomandibular disorders (TMD) and bruxism, as well as to measure masticatory performance of subjects with Charcot-Marie-Tooth type 2 (CMT2).
Methods And Results: The average number of decayed, missing, and filled teeth (DMFT) for both groups, control (CG) and CMT2, was considered low (CG = 2.46; CMT2 = 1.