Publications by authors named "Cy Chittenden"
Article Synopsis
- Eukaryotic genomes, like those in humans, often contain large arrays of satellite DNA, such as Human Satellite 3 (HSat3), that are not well understood, especially in terms of their function outside of centromere biology.
- HSat3 comprises about 2% of the human genome, forms massive arrays, and has been largely excluded from genomic studies until recently, leading to a lack of knowledge about its functional roles.
- Recent research uncovered that HSat3 has a high density of transcription factor (TF) motifs, particularly related to the Hippo signaling pathway, and reveals that the TEAD transcription factor interacts with the co-activator YAP at HSat3 regions, suggesting a novel link between
Article Synopsis
- The review focuses on toxoplasmosis rates in Panama and Colombia, analyzing data on seroprevalence and risk factors.
- Studies showed seroprevalence in Ciudad de Panamá ranged from 22% to 44%, with higher rates linked to poverty and closeness to water.
- Heat maps and mathematical models were created to pinpoint areas that need targeted healthcare campaigns for congenital toxoplasmosis and infections.
Article Synopsis
- The purpose of the review was to develop and assess educational materials aimed at reducing disease burdens from infections in Panama, Colombia, and the USA.
- Recent findings indicate that educational programs in these countries have not yet been evaluated for their effectiveness, despite being implemented for various demographics like high school students and pregnant women.
- The summary highlights that these educational materials have shown short-term benefits in disseminating information, with future goals focusing on conducting long-term studies, updating materials based on new research, and increasing access to these resources for broader public health impact.
Purpose Of Review: Review building of programs to eliminate infections.
Recent Findings: Morbidity and mortality from toxoplasmosis led to programs in USA, Panama, and Colombia to facilitate understanding, treatment, prevention, and regional resources, incorporating student work.
Summary: Studies foundational for building recent, regional approaches/programs are reviewed.
Article Synopsis
- The review discusses international efforts to create a global public health initiative for toxoplasmosis, aiming to enhance maternal and child health by preventing and treating the disease.
- Recent findings indicate that some countries are making progress in eliminating toxoplasmosis but face significant challenges.
- Key issues include the high costs and inaccessibility of diagnostic tests and treatment, especially for marginalized communities, as well as delays in essential medical procedures and insurance processes.