Introduction: Cryoglobulins are single or mixed immunoglobulins that are subject to reversible precipitation at low temperatures.
Objective: The aims of this paper were: 1. Comparison of cryoglobulin positive (CP), cryoglobulin negative (CN) heroin addicts and the control group (CG) in terms of serum immunoglobulins IgG, IgA and IgM and complement components C3 and C4; 2.