Correlation between biochemical features and outcomes of preoperative imaging (SPECT-CT and Ultrasound) in primary hyperparathyroidism.

Background: Primary hyperparathyroidism is the third most common endocrine disorder, diagnosed by elevated parathyroid hormone (PTH) in hypercalcaemia. Several biochemical factors have been described to suggest severity of disease and may be correlated with preoperative imaging.

Methods: This was a retrospective study of patients who underwent parathyroidectomy over a 3-year period.

Changing pattern of pheochromocytoma and paraganglioma in a stable UK population.

Context: Pheochromocytomas and paragangliomas (PCC/PGLs) are diagnosed variously with increasing incidence and changing clinical and pathology pattern.

Objective: The aim was to further characterize PCC/PGLs in a stable population.

Methods: A retrospective, single institution study analysed adrenalectomies for PCC/PGLs between January 2010 - January 2019.

INCIDENTAL PARATHYROIDECTOMY DURING THYROID SURGERY - RISK, PREVENTION AND CONTROVERSIES; AN EVIDENCE-BASED REVIEW.

Background: Postoperative hypocalcemia after thyroid surgery has a high prevalence ( 16-55% in different series). Incidental parathyroidectomy (IP) is a less discussed complication of thyroidectomy with consequences not properly defined. The aim of our study was to find incidence, risk factors and how to prevent IP.

RETROSTERNAL GOITRES: A PRACTICAL CLASSIFICATION.

Background: There is no standard definition for goitres extending below the thoracic inlet and no clear guidelines for pre-operative planning of surgery. The aim of this study is a practical classification of retrosternal goitres (RSG) based on the anatomical , radiological shape and size of the thyroid.

Methods: Retrospective analysis of all thyroidectomies performed in a referral centre between January 2012 and December 2016.

PRIMARY HYPERPARATHYROIDISM - STRATEGY FOR MULTIGLAND DISEASE IN THE ERA OF SPECT-CT.

Purpose: To re-examine our clinical practice and review strategy for treatment of primary hyperparathyroidism in patients with multigland disease.

Methods: Retrospective analysis of 121 consecutive primary hyperparathyroidism (PHPT) patients who underwent surgery in a tertiary center between January 2010 and December 2014.

Results: Of 121 patients with PHPT 87% had single gland adenoma (SGD) and 13% had multigland disease (MGD).

A COMPARATIVE ANALYSIS OF THE INITIAL EAST EUROPEAN CENTER EXPERIENCE WITH A WESTERN HIGH-VOLUME CENTER FOR OPEN MINIMALLY INVASIVE PARATHYROIDECTOMY (OMIP) AS TREATMENT OF PRIMARY HYPERPARATHYROIDISM.

Objective: To compare results of treatment of primary hyperparathyroidism (PHPT) in two teaching hospitals (eastern and western Europe) and to establish conclusions regarding quality of surgery for PHPT in Romania.

Methods: We reviewed two prospectively collected databases of patients submitted to open minimally invasive parathyroidectomy (OMIP) for symptomatic PHPT in two centers from Romania and the United Kingdom (UK). We included patients with biochemically proven PHPT and positive pre-operative localization studies.