Evaluation of plasma diazepam and nordiazepam concentrations following administration of diazepam intravenously or via suppository per rectum in dogs.

Objective: To evaluate the pharmacokinetics of diazepam administered per rectum via compounded (ie, not commercially available) suppositories and determine whether a dose of 2 mg/kg in this formulation would result in plasma concentrations shown to be effective for control of status epilepticus or cluster seizures (ie, 150 to 300 ng/mL) in dogs within a clinically useful interval (10 to 15 minutes).

Animals: 6 healthy mixed-breed dogs.

Procedures: Dogs were randomly assigned to 2 groups of 3 dogs each in a crossover-design study.

Retention of surgery specialists in academia: a critical agenda.

Recruitment and retention of specialists to academia appears to be a growing problem in university teaching hospitals. Members of the American College of Veterinary Surgeons (ACVS) believe that the movement of surgery specialists to practice may have an impact on the training of veterinary students and surgery residents. To address these concerns, 1,071 ACVS diplomates and 60 department heads and hospital directors from all veterinary schools in North America were surveyed to determine whether a problem exists, the extent of the problem, and potential reasons for migration of specialists to practice.

Vertical position of the patella in the stifle joint of clinically normal large-breed dogs.

Objective: To define the vertical position of the patella in clinically normal large-breed dogs.

Sample Population: Cadavers of 13 clinically normal large-breed dog.

Procedure: Both hind limbs were harvested with intact stifle joints and mounted on a positioning device that allowed full range of motion of the stifle joint.

Influence of limb positioning and measurement method on the magnitude of the tibial plateau angle.

Objective: To evaluate the effect of limb positioning and measurement technique on the magnitude of the radiographically determined tibial plateau angle (R-TPA).

Study Design: In vitro study, R-TPA was determined by 6 blinded observers and image measurement software.

Animals: Five canine cadaver hind limbs.

Comparison of tibial plateau angles in normal and cranial cruciate deficient stifles of Labrador retrievers.

Objective: To investigate tibial plateau angles (TPA) in normal and cranial cruciate ligament (CCL) deficient stifles of Labrador retrievers.

Study Design: Prospective clinical study.

Animals: Eighty-one client-owned purebred Labrador retrievers.