Publications by authors named "Curran Phillips"
Background: Age represents the largest risk factor for Alzheimer's disease (AD) but is typically treated as a covariate. Still, there are similarities between brain regions affected in AD and those showing accelerated decline in normal aging, suggesting that the distinction between the two might fall on a spectrum.
Objective: Our goal was to identify regions showing accelerated atrophy across the brain and investigate whether these overlapped with regions involved in AD or where related to amyloid.
Article Synopsis
- Large language models (LLMs) can perform various language tasks without specific training data, but their inaccurate and potentially harmful outputs limit their use in clinical settings.
- A study evaluated Almanac, an LLM framework designed for medical guidance, by comparing it with standard LLMs like ChatGPT-4, based on responses to 314 clinical questions from a panel of healthcare experts.
- Results indicated that Almanac significantly outperformed standard LLMs in factuality, completeness, user satisfaction, and safety, highlighting the need for thorough testing of these models before clinical application.